Although protein-protein interaction networks are an ubiquitous component of modern systems biology, comparatively few efforts have been made to tailor their topology to the actual cellular condition under study. Since a simple reduction of the networks to the subset of expressed genes only scratches the surface of higher organisms’ regulatory capabilities, we propose the advanced method PPIXpress that allows to exploit expression data at the transcript-level and is thus able to also reveal alterations in protein connectivity caused by alternative splicing.
The original publication can be found on https://bioinformatics.oxfordjournals.org/content/32/4/571 .

Features

  • automatic construction of protein-protein interaction networks

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License

GNU General Public License version 3.0 (GPLv3)

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Additional Project Details

Operating Systems

Linux, Mac, Windows

Languages

English

Intended Audience

Healthcare Industry, Science/Research

User Interface

Command-line, Console/Terminal, Java Swing

Programming Language

Java

Related Categories

Java Molecular Science Software, Java Bio-Informatics Software, Java Medical Software

Registered

2015-02-26