Opera

Opera (Optimal Paired-End Read Assembler) is a sequence assembly program (http://en.wikipedia.org/wiki/Sequence_assembly). It uses information from paired-end or long reads to optimally order and orient contigs assembled from shotgun-sequencing reads.

An updated version called OPERA-LG has been re-engineered with features for the assembly of large and complex genomes.

Song Gao, Denis Bertrand, Burton K. H. Chia and Niranjan Nagarajan. OPERA-LG: efficient and exact scaffolding of large, repeat-rich eukaryotic genomes with performance guarantees. Genome Biology, May 2016, doi: 10.1186/s13059-016-0951-y.

Song Gao, Wing-Kin Sung, Niranjan Nagarajan. Opera: reconstructing optimal genomic scaffolds with high-throughput paired-end sequences. Journal of Computational Biology, Sept. 2011, doi:10.1089/cmb.2011.0170.

Features

Assembly with performance guarantees
Assembly of large and complex genomes
Supports third-generation sequencing data (PacBio, Nanopore)
Assembly of repeat sequences
Improved memory and runtime efficiency

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dreamafox Posted 2013-05-31

Operasf is excellent! Thanks.
majorfriday Posted 2013-05-30

Thanks for updates ;)

2 users found this review helpful.

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Registered

2011-03-25

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