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| Name | Modified | Size | Downloads / Week |
|---|---|---|---|
| miRBond.readme.txt | 2018-12-05 | 2.1 kB | |
| pig_predicted_miRNA_targets_with_overlapping_binding_sites_and_SNPs.gz | 2018-12-05 | 1.9 MB | |
| pig_predicted_miRNA_targets_with_overlapping_binding_sites.gz | 2018-12-05 | 9.0 MB | |
| cow_predicted_miRNA_targets_with_overlapping_binding_sites_and_SNPs.gz | 2018-12-05 | 2.7 MB | |
| pig_miRNAs_including_SNPs.gz | 2018-12-05 | 673 Bytes | |
| cow_predicted_miRNA_targets_with_overlapping_binding_sites.gz | 2018-12-05 | 15.4 MB | |
| chicken_predicted_miRNA_targets_with_overlapping_binding_sites_and_SNPs.gz | 2018-12-05 | 3.1 MB | |
| cow_miRNAs_including_SNPs.gz | 2018-12-05 | 1.9 kB | |
| chicken_predicted_miRNA_targets_with_overlapping_binding_sites.gz | 2018-12-05 | 27.9 MB | |
| chicken_miRNAs_including_SNPs.gz | 2018-12-05 | 914 Bytes | |
| Totals: 10 Items | 60.0 MB | 0 |
Welcome to miRBond ============================== Introduction ============================== Domestic animals show considerable genetic diversity. Previous studies suggested that animal phenotypes were affected by miRNA-mRNA interplay, but these studies focused mainly on the analysis of one or several miRNA-mRNA interactions. Whereas in this study, we present miRNA-mRNA and miRNA-lncRNA interactions on genome scale by using the miRanda and TargetScan algorithms. There has been strong directional artificial selection practiced during the domestication of animals. Thus, we investigated the SNPs that were located in miRNAs and miRNA binding sites and found several SNPs located in 3¡¯-UTR of mRNA had potential to disturb the miRNA-mRNA interactions. In addition, a database, named miRBond, was developed to provide visualization, analysis and downloading of the resulting datasets. Our results open the way to further experimental verification of miRNA-mRNA and miRNA-lncRNA interactions, and SNPs¡¯ influence upon such interplay. ============================== Download ============================== Pig (Sus scrofa, assembly SS_10.2) -- pig_predicted_miRNA_targets_with_overlapping_binding_sites.gz -- pig_predicted_miRNA_targets_with_overlapping_binding_sites_and_SNPs.gz -- pig_miRNAs_including_SNPs.gz Chicken (Gallus gallus, assembly GG_4.0) -- chicken_predicted_miRNA_targets_with_overlapping_binding_sites.gz -- chicken_predicted_miRNA_targets_with_overlapping_binding_sites_and_SNPs.gz -- chicken_miRNAs_including_SNPs.gz Cow (Bos taurus, assembly UMD_3.1) -- cow_predicted_miRNA_targets_with_overlapping_binding_sites.gz -- cow_predicted_miRNA_targets_with_overlapping_binding_sites_and_SNPs.gz -- cow_miRNAs_including_SNPs.gz ============================== Contact us ============================== Aimin Li, PhD School of Computer Science and Engineering, Xi'an University of Technology, 5 South Jinhua Road, Xi'an, Shaanxi 710048, P.R China liaiminmail AT gmail.com emanlee815 AT 163.com ==============================
