Marine bacteria are the most widely distributed organisms in the ocean environment and produce all kinds of compounds due to their complex metabolism. With the support from the China Mineral Resources Research and Development Association (COMRRDA12SC01 and COMRRDA12SC02), a chemical database based on secondary metabolite profiles of marine bacteria together with an LC-MS matching software have been developed by Coastal Marine Laboratory (CML) of HKUST. >1000 bacterial strains collected from different marine environment have been successfully cultured and their secondary metabolites were analyzed by LC-MS and imported to database. This database and related software provide a new strategy for natural product screening and a complementary approach to current methods for marine bacteria identification.

Features

  • Chemical fingerprint comparison of marine bacteria
  • species-specific metabolite discovery
  • secondary metabolite distribution in different marine bacteria
  • reduction of rediscovering natural products from marine bacteria

Project Samples

Marine bacteria metabolite database

Project Activity

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Registered

2014-01-23
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