We have developed a lung cancer screening panel based on the occurrence of specific clonal hematopoietic mutations in peripheral blood samples. The software provided here can be used to predict the probability of cancer from peripheral blood samples. The sequencing data from the blood sample should be first aligned to the GRCh38 reference genome using the Burroughs-Wheeler aligner and variants called using the Mutect2 for variant calling. The resulting VCF file is used as input to the software.
Output: Predicted probability of cancer.
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