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We developed a universal approach and tool designated Geptop, based on orthology and phylogeny, to offer gene essentiality annotations. The web server and standalone version of Geptop are available at http://cefg.uestc.edu.cn/geptop/ free of charge. This package is dependent on Python, Biopython and BLAST+.
Citation: Wei W, Ning L-W, Ye Y-N, Guo F-B (2013) Geptop: A Gene Essentiality Prediction Tool for Sequenced Bacterial Genomes Based on Orthology and Phylogeny. PLoS ONE 8(8): e72343. doi:10.1371/journal.pone.0072343
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