This is on the latest windows server version and the latest windows client version (v2.8.81).
When using a modern mouse that has scrollwheel tilt left and tilt right capabilities, the clicks are not transmitted to the remote machine.
How to Reproduce:
Open this URL in your browser, both on your local machine and on the remote desktop machine.
https://codepen.io/jaemskyle/pen/XWJvRL
Now use your mouse scrollwheel tilt to scroll left/right.
On your local desktop, the yellow box does scroll, on the remote desktop, it is not.
Thanks.