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From: Vince F. <for...@gm...> - 2012-10-17 20:21:18
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qctool (http://www.well.ox.ac.uk/~gav/qctool/#overview) looks like the right tool. On Tue, Oct 16, 2012 at 5:04 PM, Vince Forgetta <for...@gm...> wrote: > Hi, > > Is there a tool chain to convert IMPUTE2 data (.gen and .sample files) > to VCF format, while still retaining dosage values? For example, as a > GL formatted genotype. > > So far, I have come up with: > > 1. IMPUTE2 to PED using GTOOL > 2. PED to binary PED using PLINK > 3 .binaryPED to VCF using PLINKSEQ. > > But GTOOL thresholds the genotypes to integers. > > Thanks in advance for the help. > > Vince |