On OS X v10.8.5, the forward search (editor -> internal viewer) with CMD + left mouse click works fine. But the inverse search does not work. Instead, pressing CMD + left click has the same effect as left click, which is to scroll down the PDF. Inverse search via the context menu does work, so this appears to be an issue with the shortcut.
Works here. Which version of TXS are you using?
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Last edit: Tim Hoffmann 2015-06-21