RPlite

Rank Product is a non parametric methodology introduce by Breitling et al. for differential expression analysis. It allows the user to perform meta-analysis of different transcriptomic datasets (with different protocols, platforms, technologies, batch, etc.).
This implementation computes both up and down regulations in one pass. It is parallelized (dependency: parallel) and memory-optimized: the user can specify the maximum size of the matrices in memory (parameter size) for the unpaired test.