One outstanding issue with the host software is it's incompatibility with 64-bit Linux. The Wiki currently recommends to replace some of the distributes libraries with those installed by the packaging system: http://reprap.org/wiki/Installing_RepRap_on_your_computer#Linux_AMD64 . This could be simpler if the RepRap host software would just prefer installed libraries over those coming with RepRap in general.
Please find a patch attached. Tested and verified to work fine on 64-bit Ubuntu.