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The software builds 3D models of chromosomes or genome given chromosomal contacts data such as Hi-C, TCC, 5C. MOGEN was tested on simulated datasets. Using real Hi-C data of a human cell line, MOGEN built models that are consistent with knowledge about the genome of the cell line.
Detail on how to use it: https://github.com/BDM-Lab/MOGEN
It is published in Bioinformatics: http://bioinformatics.oxfordjournals.org/content/32/9/1286
Bioinformatics, Data Mining, Machine Learning (BDM) Laboratory,
Jianlin Cheng, PhD
Department of Computer Science
University of Missouri, Columbia
Email: chengji@missouri.edu
Features
- 3D genome, chromosome modeling
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