Re: [Mged-ontologies] question about QuantitationType

[Helen P. <par...@eb...>]

Hi Eugene,

if the data is simply averaged across multiple 
arrays then it should be DerivedBioAssayData.

the Definition (in MAGE) of BADCluster is:
describes a mathematical method of higher level 
analysis whereby BioAssayData objects are grouped 
together into nodes.

I infer from this that you need the 
DerivedBioAssayData before you can apply higher 
level analysis. And BioassayDataCluster refers 
specifically to clustering methods (at least in 
the MAGE docs) not other transformations.

DerivedSignal

MAGE docs say that:
is a calculated measurement of the intensity of a 
signal after a transformation involving 
normalization and/or replicate design elements

which I understand to mean that values computed 
across mutiple DBA's are only DerivedSignal if 
they are intensities and not of they are other types.


regards

Helen





Chudin, Eugene wrote:

> I am new to MAGE-ML and trying to learn more about it. 
> The question I have is about  representing data derived from multiple arrays (e.g. average Feature intensity across multiple arrays)?
> Should one use DerivedBioAssayData or BioAssayDataClusters?
> In terms of QuantitationType, are all signals computed from multiple arrays by definition DerivedSignal objects? 
> 
> 
> Thank you,
> Eugene Chudin
> 
> 
> 
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