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VIGOR - Viral Genome ORF Reader

VIGOR (Viral Genome ORF Reader) is a perl application to predict protein sequences encoded in viral genomes. VIGOR was written for The JCVI Genomic Sequencing Center for Infectious Diseases (GSCID) at The J. Craig Venter Institute is sponsored by the National Institute of Allergy and Infectious Diseases.

VIGOR determines the protein coding sequences by sequence similarity searching against curated viral protein databases.

Supported Viruses

VIGOR currently annotates the following viruses:

• Alphaviruses

• Bunyaviridae

• Coronavirus (Alpha/Beta/Gamma/Delta/Unclassified Cov)

• Filoviridae (Ebola and Marburg)

• Human Rhinovirus/Enterovirus

• Human Adenovirus (A,B,C,D,E,F,G)

• Human Herpesvirus 5

• Influenza (A, B and C for human, avian, and swine)

• Measles/ Morbillivirus

• Metapneumovirus

• Mumps / Rubulavirus

• Norovirus (I, II, misc, murine)

• Rabies

• Respiratory Syncytial virus (RSV)

• Respirovirus (HPIV-1, HPIV-3, Sendai)

• Rotavirus

• Rubella

• Sapovirus

• Varicellovirus

• Yellow Fever / Japanese encephalitis (JEV)

Publications

The VIGOR software has been published under the following publications:

1. VIGOR, an annotation program for small viral
   genomes. Shiliang Wang, Jaideep P. Sundaram, David Spiro, BMC Bioinformatics 2010

2. VIGOR extended to annotate genomes for
   additional 12 different viruses. Shiliang Wang, Jaideep P. Sundaram and Timothy B. Stockwell, Nucleic Acids Research 2012