HipMer

HipMer is the first end-to-end de novo genome assembler designed for extreme scale analysis via efficient parallelization. The single-genome assembly implementation is a high-performance parallelization and port of the Meraculous assembler (http://jgi.doe.gov/data-and-tools/meraculous/). The MetaHipMer extension is a recent addition to HipMer that is geared to large metagenomes and leverages iterative kmer sizes and a specialized scaffolding algorithm to produce increased contiguity and accuracy in metagenomic assemblies. It is able to reconstruct rRNA elements via a separate algorithm which relies on reference SSU and LSU Hidden Markov Models to help traverse the contig graph around ribosomal RNA regions.

For more information and publications visit the HipMer Portal (http://portal.nersc.gov/project/hipmer/)

MetaHipMer is one component of the ExaBiome project (https://sites.google.com/lbl.gov/exabiome/home), part of the Exascale Computing Project: https://www.exascaleproject.org/