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GeneNetWeaver (GNW) is an open-source tool for in silico benchmark generation and performance profiling of network inference methods. GNW was used to generate the community-wide DREAM3, DREAM4 and DREAM5 In Silico Challenges.
Features
- Extraction of modules from known transcriptional regulatory networks (E.coli, Yeast, etc.)
- Generation of realistic in-silico gene network benchmarks for network inference methods
- Simulation of realistic biological experiments (knowckout, knockdown, dual-knockout, multifactorial perturbations, time series, etc.)
- Performance evaluation of network predictions (Precision-Recall, ROC, motif analysis)
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Categories
Bio-InformaticsLicense
MIT LicenseFollow GeneNetWeaver
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