The only way to enter menu is F1 key. If your keyboard is lacking function keys, you have to use spare one just to be able to get into it.
Idea: add shortcut (for example CapsShift + SybolShift + Enter) to pop-up main menu beside the F1 key. And, once the menu is open, also use CapsShift + 1 (Edit) to close it (similar to ESC key action). It would be also nice to support arrow keys (up/down - CapsShift + 6, 7) to navigate menu, but it's not necessary due to shortcut letters.
I hope it's an easy fix and will help to everyone using non-standard PC keyboard or Recreated ZX Spectrum keyboard.