The COMER method based on sequence profile-profile comparison is one of the most sensitive and accurate computational tools developed for protein alignment and homology search. COMER version 2.1 (COMER2) represents one of the fastest implementations of calculations for sensitive protein homology search. High COMER2 performance is achieved by harnessing the power of the Graphics processing unit (GPU). Hence, a GPU is expected to be installed on the system.
The files include the compressed source code and associated and accompanying files for use with COMER2. The source code is also available on GitHub (https://github.com/minmarg/comer2).
COMER2 is licensed under GNU General Public License version 3. Please find the LICENSE and COPYING files included in the software package.
Funding: This work was supported by the European Regional Development Fund [grant number 01.2.2-LMT-K-718-01-0028].
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