Menu

#2413 CHEBI:42164, please check

None
closed
None
5
2015-10-30
2015-01-15
No

Hi,

(S)-2,3-diaminopropanoate(1+), needed for the new IUBMB reaction:
ATP + fumarate + (S)-2,3-diaminopropanoate = AMP + diphosphate + N3-fumaroyl-(S)-2,3-diaminopropanoate

Please also add x-ref to MetaCyc: L-23-DIAMINOPROPANOATE

/Kristian

Discussion

  • Steve Turner

    Steve Turner - 2015-01-19
    • status: open --> pending
    • assigned_to: Steve Turner
    • Group: -->
     
  • Steve Turner

    Steve Turner - 2015-01-19

    Hi Kristian,

    I've created CHEBI:84374 which has the compound with the overall charge of +1 with both the amino groups protonated and a negatively charged carboxy group (the other one, 42164 only has the side-chain amino group protonated). However, according to our version of Marvin (6.1.5) the major species at pH 7.3. is actually the neutrally charged zwitterionic compound, CHEBI:57721. I don't know what species version 6.2.0 gives. This may affect balancing the reaction as the N-fumaroyl derivative will almost certainly have the alpha-amino group protonated. Anyway, both options are in there.

    Cheers,
    Steve

     
  • Steve Turner

    Steve Turner - 2015-10-30
    • status: pending --> closed
     
MongoDB Logo MongoDB