[Bio-bwa-help] BWA-MEM
Status: Beta
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From: Fatih T. <ftu...@gm...> - 2017-03-03 11:03:44
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Dear all, I have been looking for some documentation about BWA-MEM algorithm which, according to manual page, does not have an official publication yet. Is there any document that explains/shows the details about it? For instance, what are the things common between MEM and BWA-SW (and BWA backtrack) in terms of the steps followed (as explained in Li&Durbin '9 and '10)? I got this info from BWA's SF page : The BWA-MEM algorithm is based on an algorithm finding super-maximal exact matches (SMEMs), which was first published with the fermi assembler paper in 2012. I first implemented the basic SMEM algorithm in the fastmap command for an experiment and then extended the basic algorithm and added the extension part in Feburary 2013 to make BWA-MEM a fully featured mapper. Thanks a lot in advance. -- Fatih |