[Bio-bwa-help] clarification on color-space support in BWA 0.6.1
Status: Beta
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From: Phillipe L. <Phi...@je...> - 2012-06-08 17:18:13
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I saw the following in the NEWS file of BWA 0.6.1. While it looks like color-space alignment is now disabled in BWA-short, what about BWA-SW? Is color-space still enabled and working there? I found the following thread 'http://kevin-gattaca.blogspot.com/2011/11/bio-bwa-help-color-space-support-may-be.html' which mentions that color-space support is dropping in 0.6, but from below want to confirm if it's being dropped from BWA-short, BWA-SW, or both. Thanks you, Phillipe Release 0.6.1 (28 November, 2011) ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Notable changes to BWA-short: * Bugfix: duplicated alternative hits in the XA tag. * Bugfix: when trimming enabled, bwa-aln trims 1bp less. * Disabled the color-space alignment. 0.6.x is not working with SOLiD reads at present. Notable changes to BWA-SW: * Bugfix: segfault due to excessive ambiguous bases. * Bugfix: incorrect mate position in the SE mode. * Bugfix: rare segfault in the PE mode * When macro _NO_SSE2 is in use, fall back to the standard Smith-Waterman instead of SSE2-SW. * Optionally mark split hits with lower alignment scores as secondary. Changes to fastmap: * Bugfix: infinite loop caused by ambiguous bases. * Optionally output the query sequence. (0.6.1: 28 November 2011, r104) |