The FreeMIS project is an Open Source, web based, Management Information System for high schools. It has recently been ported to the new Ruby on Rails web development framework. Initially the development will focus on the requirements of UK schools.
SilverStripe is a Web Framework and Content Management System. It differs from many of the better known CMSes in that it uses fully object oriented code, has native Ajax support, and allows you to very cleanly customize the system to suit your needs.
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iWiccle is an online Web 2.0 platform. innovative builders specializing in social networks, blogging sites, web communities, gallery presentations, link directories, & article portals. A universal web community script written in PHP & MySQL. New v1.3
Karrigell is a flexible Python web framework, with a clear and intuitive syntax. It is independant from any database, ORM or templating engine, and lets the programmer choose between a variety of coding styles
BixChange is a framework for web-based development. It is written in Perl and is designed to run in either CGI or mod_perl environments under the Apache webserver.
A fork of the Toast project which is a controller unit testing add-on for the CodeIgniter web framework. ToastX adds more graphical information and test tracking.
The Virtual Commons (http://commons.asu.edu) is an open software initiative devoted to computational experiments on collective action and resource governance and funded by Arizona State University's Center for Behavior, Institutions, and the Environment (http://cbie.asu.edu).
NOTE: we've moved our development to GitHub at https://github.com/virtualcommons - please look for the latest versions there.
Zonk! is a lightweight skeleton web application framework implementing the hierarchical model-view-controller design pattern (HMVC) made for Apache web servers running PHP5.
The BlazeFramework is a Java like Framework which provides a nice API for developers. It offers developers a real OOP feeling in PHP like in Java. It's an event-based MVC web framework which uses XML for view definitions and the navigationsystem.
A PHP web application framework centered around a page/control/rpc server model with a framework for modules and permissions. Support for OpenID/Facebook Connect included. All data is persisted in a JSON object store, so no SQL server is required.