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wxFormBuilder is a GUI builder for the wxWidgets framework. Code generation is supported for C++, Python, Lua and PHP. Additionally, the import and export of XRC code is possible. To support additional widgets, custom plugins can be used. wxFormBuilder runs on Windows, various Linux distributions and macOS.
Graphical User Interface Toolkit for Python with minimal dependencies
...DPG offers a solid framework for developing scientific, engineering, gaming, data science and other applications that require fast and interactive interfaces. The Tutorials will provide a great overview and links to each topic in the API Reference for more detailed reading. Complete theme and style control. GPU-based rendering and efficient C/C++ code.
Olex2 is visualisation software for small-molecule crystallography developed at Durham University/EPSRC. It provides comprehensive tools for crystallographic model manipulation for the end user and an extensible development framework for programmers. The project has been supported by Olexsys Ltd since 2010.
ACDK - Artefaktur Component Development Kit - is a platform independent C++-framework similar to Java or C#/.NET for generating distributed and scriptable components and applications.
Educational game framework supporting board games, strategy games, and other grid-based game boards. Currently uses Python/wxPython as the application language/library. C++ libs included to help create AI for the various games.
Baum is a Qt based GUI application framework with a built in python interpreter. Baum allows rapid creation of GUI's with simple python scripts. Programmers can re-use available python and widget library.