Pydub
Manipulate audio with a simple and easy high level interface
...Note that no validation takes place on these parameters, and you may be limited by what your particular build of ffmpeg/avlib supports. You can open and save WAV files with pure python. For opening and saving non-wav files, like mp3, you'll need ffmpeg or libav. Any operations that combine multiple AudioSegment objects in any way will first ensure that they have the same number of channels, frame rate, sample rate, bit depth, etc.