Search Results for "genome"
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Showing 14 open source projects for "genome"
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CpDB
Relational database schema and tools for bacterial genome annotation
This software allows us to create a relational database in PostgreSQL hosting full bacterial genomes. Besides the database, there is software, like a parser, to convert EMBL or GBK files to the CpDB relational schema. Once in the CpDB, one can extract unlimited reports from bacterial genomes using SQL. This software is part of the Ph.D. in Bioinformatics from Anderson Santos (https://orcid.org/0000-0003-3418-0823) developed under the Corynebacterium pseudotuberculosis (Cp) pangenome project.... -
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ClustAGE is a command-line tool built using the Perl scripting language for the purpose of analyzing and comparing accessory genomic elements (AGEs) between genomes. It takes as input sets of AGE nucleotide sequences previously identified from the genome sequences of two or more separate organisms. These AGE sequence sets can be extracted from complete or draft whole-genome nucleotide sequences using the previously-developed software tools Spine (https://github.com/egonozer/Spine) and AGEnt (https://github.com/egonozer/AGEnt). See README (https://sourceforge.net/p/clustage/code/ci/master/tree/README.md) for more information.
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Tofu
Tofu is a Python tool for generating synthetic UK Biobank data
...The study has collected and continues to collect extensive phenotypic and genotypic detail about its participants, including data from questionnaires, physical measures, sample assays, accelerometry, multimodal imaging, genome-wide genotyping and longitudinal follow-up for a wide range of health-related outcomes. Tofu will generate synthetic data which conforms to the structure of the baseline data UK Biobank sends researchers by generating random values. For categorical variables (single or multiple choices), a random value will be picked from the UK Biobank data dictionary for that field. ... -
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GATOOL - Genome Assembly Tool
The tool allows to perform a bacterial genome assembly.
GATOOL is a web interface whichs integrates several tools, with the purpose of to do a genome assembly task and provide to the users a nice and real experience. and a very fast way to genomes assembly. -
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PingPongPro
Find ping-pong signatures like a pro
...Please refer to: https://github.com/suhrig/pingpongpro Piwi-interacting RNAs (piRNAs) are a class of small non-coding RNAs, predominantly active in the germ line. There, they limit the detrimental effect of transposons on the genome. They do so by forming a complex with Piwi proteins. The complex binds and then cleaves mRNA molecules of active transposons. The resulting mRNA fragments induce the production of more piRNAs, thus reinforcing the anti-transposon response in a feed-forward loop called the "ping-pong cycle". A key question in ping-pong cycle research is identification of piRNAs which are amplified through the cycle. ... -
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COPEread
Connecting Overlapped Pair-End Reads
COPE (Connecting Overlapped Pair-End reads) is a method to align and connect the illumina sequenced Pair-End reads of which the insert size is smaller than the sum of the two read length.The connected reads can be used in genome assembly, resequencing and transcriptome research. The full citation: COPE: An accurate k-mer based pair-end reads connection tool to facilitate genome assembly Binghang Liu; Jianying Yuan; Siu-Ming Yiu; Zhenyu Li; Yinlong Xie; Yanxiang Chen; Yujian Shi; Hao Zhang; Yingrui Li; Tak-Wah Lam; Ruibang Luo Bioinformatics (2012) 28(22): 2870-2874; doi: 10.1093/bioinformatics/bts563 -
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SOAPdenovo2
Large-size genome de-novo assembler
What's next of SOAPdenovo2: MEGAHIT is the formal successor of SOAPdenovo2 MEGAHIT: An ultra-fast single-node solution for large and complex metagenomics assembly via succinct de Bruijn graph http://www.ncbi.nlm.nih.gov/pubmed/25609793 https://github.com/voutcn/megahit Latest Code on GitHub: https://github.com/aquaskyline/SOAPdenovo2 SOAPdenovo is a novel short-read assembly method that can build a de novo draft assembly for human-sized genomes. The program is specially designed... -
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CupidTool
Cupid: simultaneous reconstruction of miRNA-target and ceRNA networks
Chiu et. al., Genome Research 2014 Cupid is a method for simultaneous prediction of miRNA-target interactions and their mediated competitive endogenous RNA (ceRNA) interactions. We showed that our integrative approach significantly improves on miRNA-target prediction accuracy as assessed by both mRNA and protein level measurements in breast cancer cell lines. -
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CUSHAW2: Parallel Gapped Read Alignment
One of the leading short-/long-read aligner to large genomes
CUSHAW2 is a fast and parallel gapped read alignment to large genomes, such as the human genome. The performance evaluation, by aligning simulated and real datasets to the human genome, shows that CUSHAW2 is consistently among the highest-ranked aligners in terms of alignment quality for both single-end and paired-end alignment, while demonstrating highly competitive speed. Furthermore, our aligner shows good parallel scalability with respect to the number of CPU threads. -
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quadGT
Software package for the joint genotyping
quadGT is a software package for the joint genotyping of two parents, child’s normal genome and child’s tumor genome based on sequencing reads aligned to a reference genome. -
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BCP
NGS analysis tool
...It is oriented mainly towards targeted resequencing experiments, with a set of functions for general purposes. BCP also includes a function for breast cancer risk estimation, based on the Gail model, using both clinical and genome data. -
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genomeLD is a novel bioinformatic tool to simulate linkage disequilibrium (LD) patterns and SNPs for genome-wide association studies.
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Contains various algorithms that maps short reads produced from Illumina (Solexa) Genome Analyzer, or Applied Biosystems' SOLiD System, to a reference sequence or a set of reference sequences.
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