Showing 63 open source projects for "throughput"

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  • 1
    kallisto

    kallisto

    Near-optimal RNA-Seq quantification

    kallisto is a program for near-optimal quantification of transcript abundances from RNA-Seq data, or more generally of target sequences using high-throughput sequencing reads. It is based on the idea of using pseudoalignment to quickly determine reads and targets’ compatibility, with no need for alignment. According to benchmarks done on a Mac desktop computer, kallisto can quantify 30 million human bulk RNA-seq reads in less than 3 minutes with just the read sequences and a transcriptome index, that in itself can take more than 10 minutes to build. ...
    Downloads: 4 This Week
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  • 2
    Bowtie 2

    Bowtie 2

    A fast and sensitive gapped read aligner

    ...It is widely used in bioinformatics pipelines for RNA-seq, DNA-seq, metagenomics, variant analysis, and other sequencing-based research tasks. Overall, Bowtie 2 remains a foundational command-line tool for high-throughput sequence alignment and reproducible computational biology workflows.
    Downloads: 3 This Week
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  • 3
    RobotsTxt

    RobotsTxt

    The repository contains Google's robots.txt parser

    This is a high-performance, production-tested library for parsing and evaluating robots.txt rules against crawler user agents. It implements the core semantics of the Robots Exclusion Protocol: user-agent sections, Allow/Disallow directives, wildcard handling, and precedence rules. The code is optimized for speed and low memory so large crawls can evaluate millions of URLs quickly. It also focuses on correctness—edge cases like overlapping patterns and longest-match resolution are handled...
    Downloads: 0 This Week
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  • 4
    Train Traffic Simulator

    Train Traffic Simulator

    A game about station masters job , managing trains which are arriving

    ...Trains are created at different intervals of time with some metadata , the player is supposed to modify the signals and the switches to stop trains at the station or let them pass without any interruption. The goal will be to prevent delays , achieve maximum throughput and most importantly not cause collisions .
    Downloads: 0 This Week
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  • 5
    Chem-Parser

    Chem-Parser

    Molecule Sketcher and Immediate Parser to Excel, .SMI and 3D SDF

    ...By enabling rapid structure-to-data mapping, Chem-Parser significantly reduces manual effort in dataset preparation, ensuring consistency and accuracy across large compound libraries. Whether you're building predictive models or managing compound repositories, Chem-Parser offers a user-friendly interface and high-throughput parsing capability that makes it an indispensable addition to any researcher's toolkit. A must-have tool for computational chemists, medicinal chemists, and data scientists involved in drug discovery and molecular
    Downloads: 2 This Week
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  • 6
    NGSEP

    NGSEP

    NGSEP (Next Generation Sequencing Experience Platform)

    NGSEP is an integrated framework for analysis of short and long DNA high throughput sequencing reads. The current version provides functionalities for both de-novo and reference guided analysis of sequencing data, including genome assembly, read mapping, variants detection and genotyping and de-novo analysis of data generated from reduced representation protocols. NGSEP also provides modules for analysis of genomic variation databases (VCF files), including functional annotation, filtering, format conversion, comparison, clustering, imputation, introgression analysis and different kinds of statistics. ...
    Downloads: 1 This Week
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  • 7
    FastQC

    FastQC

    A quality control analysis tool for high throughput sequencing data

    FastQC is a quality control analysis tool designed to spot potential problems in high throughput sequencing datasets. Its goal is to provide a simple way by which to check the quality of raw sequence data coming from high throughput sequencing pipelines. It does this by running a modular set of analyses on one or more raw sequence files in fastq or bam format. It then produces a report summarizing the results, and highlighting any areas where the library may appear unusual. ...
    Downloads: 33 This Week
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  • 8
    OmicSelector

    OmicSelector

    Feature selection and deep learning modeling for omic biomarker study

    OmicSelector is an environment, Docker-based web application, and R package for biomarker signature selection (feature selection) from high-throughput experiments and others. It was initially developed for miRNA-seq (small RNA, smRNA-seq; hence the name was miRNAselector), RNA-seq and qPCR, but can be applied for every problem where numeric features should be selected to counteract overfitting of the models. Using our tool, you can choose features, like miRNAs, with the most significant diagnostic potential (based on the results of miRNA-seq, for validation in qPCR experiments).
    Downloads: 0 This Week
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  • 9
    sRNAWorkbench

    sRNAWorkbench

    The UEA sRNA Workbench

    ...Including expression profiling of known mirco RNA (miRNA), identification of novel miRNA in deep-sequencing data and identification of other interesting landmarks within high-throughput genetic data
    Downloads: 3 This Week
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  • 10

    MToolBox

    A bioinformatics pipeline to analyze mtDNA from NGS data

    MToolBox is a highly automated bioinformatics pipeline to reconstruct and analyze human mitochondrial DNA from high throughput sequencing data. MToolBox includes an updated computational strategy to assemble mitochondrial genomes from Whole Exome and/or Genome Sequencing (PMID: 22669646) and an improved fragment-classify tool (PMID:22139932) for haplogroup assignment, functional and prioritization analysis of mitochondrial variants. MToolBox provides pathogenicity scores, profiles of genome variability and disease-associations for mitochondrial variants. ...
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    Downloads: 16 This Week
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  • 11
    De_Lux

    De_Lux

    Deconvolution of luminescence cross-talk in microplate reader data

    An algorithm to deconvolve the luminescence cross-talk in high-throughput gene expression profiling to recover the true luminescence activity of a microplate.
    Downloads: 0 This Week
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  • 12

    Root Phenotyping Suite

    Three different software tools for phenotyping plant root images

    RootAnalyzer is a fully automated tool, for efficiently extracting and analyzing anatomical traits from root-cross section images. RootAnalyzer segments the plant root from the image's background, classifies and characterizes the cortex, stele, endodermis and metaxylem, and produces statistics about the morphological properties of the root cells and tissues. RTipC is a system for the fully automated detection and classification of root tips in root images obtained either by 2d flat bed...
    Downloads: 0 This Week
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  • 13
    High-Throughput Tabular Data Processor
    HIGH-THROUGHPUT TABULAR DATA PROCESSOR (HTDP) is Java application that is intended to facilitate data exploration and reduction tasks in large text files resulting from high throughput technologies, e.g. massively parallel sequencing or microarrays. The software has been optimized for microarray and deep parallel sequencing data, however it can accept any character delimited tabular data sets.
    Downloads: 0 This Week
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  • 14
    Open3DQSAR
    Open3DQSAR is a free, open-source tool written in C aimed at pharmacophore exploration by high-throughput chemometric analysis of molecular interaction fields (MIFs).
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    Downloads: 6 This Week
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  • 15
    Open3DGRID
    An open-source software aimed at high-throughput generation of molecular interaction fields (MIFs)
    Downloads: 0 This Week
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  • 16
    DockoMatic is a GUI application that is intended to ease and automate the creation and management of AutoDock jobs for high throughput screening of ligand/receptor interactions.
    Downloads: 0 This Week
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  • 17
    REHUNT

    REHUNT

    REHUNT (Restriction Enzymes HUNTing)

    REHUNT (Restriction Enzymes HUNTing) is a free and open source package implemented in JAVA for providing many useful methods for biological sequence analysis (especially in SNP genotyping) around restriction enzymes. All academic researchers are encouraged to use REHUNT in their studies or to integrate it into their systems and applications. Non-academic users or commercial needs are also welcome to use it. For further information or additional applications, please contact the author...
    Downloads: 0 This Week
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  • 18
    We developed a systematic algorithmic solution for quantitative drug sensitivity scoring (DSS), based on continuous modeling and integration of multiple dose-response relationships in high-throughput compound testing studies. License: The DSS R-package is made available under the terms of the GNU General Public License, which means that the source code is freely available for use within other software, but if you alter the code and distribute it, you must make the new source code freely available as well. This software is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY. ...
    Downloads: 1 This Week
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  • 19
    VCF Explorer

    VCF Explorer

    A desktop application for analyzing whole genome VCF files

    he decreasing cost high-throughput technologies led to a number of sequencing projects consisting thousands of whole genomes. The paradigm shift from exome to whole genome brings a significant increase in the size of output files. Most of the existing tools which are developed to analyze exome files are not adequate for large VCF files produced by whole genome studies.
    Downloads: 7 This Week
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  • 20
    Combenefit

    Combenefit

    Synergy analyses of drug and other other agent combinations

    Combenefit software is a standalone application for Windows that performs surface analyses of drug and other agent combinations to identify synergy. Please cite as: "Di Veroli,G.Y. et al. (2016) Combenefit: an interactive platform for the analysis and visualization of drug combinations. Bioinformatics." (http://bioinformatics.oxfordjournals.org/content/early/2016/05/27/bioinformatics.btw230.abstract) Current version...
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    Downloads: 60 This Week
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  • 21

    MetaOpen

    Metabolomics Bioinformatics Tools

    Our bioanalytical research exploits practical and efficient high-throughput technologies for the analyses of complex mixtures derived from living systems. This will facilitate the development of preventive, predictive and personalized medicine for specific diseases and will promote health and wellness. We use a number of high-throughput analytical platforms including multidimensional liquid chromatography-mass spectrometry (MDLC-MS) for proteomics, and for metabolomics; liquid chromatography-mass spectrometry (LC-MS), and comprehensive two-dimensional gas chromatography-mass spectrometry (GCxGC/TOF-MS). ...
    Downloads: 0 This Week
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  • 22

    Bamformatics

    Toolkit and GUI for sequencing data analysis

    The Bamformatics project aims to provide a coherent and consistent approach to analysis of high-throughput sequencing data. Its toolkit includes, among others, programs to identify variants and to compute various types genomic tracks. It also provides a graphical user interface to facilitate general bioinformatic workflows. The project wiki contains further details.
    Downloads: 0 This Week
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  • 23

    iCAS - An Illumina Clone Assembly System

    An Illumina clone assembly system using SOAPdenovo and ABySS

    Clone-by-clone sequencing, as a means of achieving high quality assemblies for large and complex genomes, continues to be of great relevance in the era of high throughput sequencing. However, assemblies obtained using current whole genome assemblers are often fragmented and sometimes have issues of genome completeness owing to different data characteristics introduced by multiplexed sequencing. With iCAS the data filtering process is based on a novel kmer frequency algorithm, resulting in near perfect pre-assembly reads. ...
    Downloads: 0 This Week
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  • 24

    HTSeq

    Analysing high-throughput sequencing data with Python

    This SourceForge page is outdated! HTSeq has been moved to github: https://github.com/simon-anders/htseq General information and documentation on HTSeq; http://www-huber.embl.de/users/anders/HTSeq
    Downloads: 0 This Week
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  • 25
    Downloads: 47 This Week
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