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MCX is a GPU-accelerated, general-purpose, physically-accurate and feature-rich 3-D light transport simulator. It is one of the fastest simulators because it can use tens of thousands of GPU threads to simulate photons in parallel.

...reconstruction part was described in: BMC Bioinformatics. 2007 Aug 6;8:288. "TomoJ: tomography software for three-dimensional reconstruction in transmission electron microscopy."Messaoudi C et al

...The user can select which available OpenCL hardware and drivers are to be used. The Package offers new numeric data types with many built-in operations (e.g., overloaded operators). It is flexibly extendible by user-written OpenCL C programs. The Package does not, by itself, provide parallelization of higher numerical methods (like BLAS or LAPACK). The Package is also available from the corresponding Octave Forge webpage https://octave.sourceforge.io/ocl/index.html. More information on GNU Octave can be found at https://www.octave.org.

This kernel uses a discrete approach where the geometry is split into "atoms" at a fixed resolution (e.g. 1µm). The aim is to make full use of the parallel processing capabilities of modern graphics hardware.