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GenoCline is a free Java software for genetic cline analysis
Identification of clines from allele frequency or genome-wide databases. Angular transformation. Sigmoid function.
Parameterization of a cline: orientation, Pearson’s product-moment correlation coefficient, linear and sigmoid regression and coefficient of determination. Graphical representation of the cline. Confidence limits.
Spatial autocorrelation. Moran's index.
Isolation by distance. Exponential regression. Correlation Fst/Distance.
Centroid method.
Cline's expected vs. predicted heterozygosity.
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Simulates data from a gaussian/beta/piecewise-linear species response function on an environmental gradient, with different sampling (error) distributions. See "Cline (biology)" on wikipedia.org.