Crystal Space is an Open Source 3D SDK for Unix, Windows, and MacOS/X. It renders with OpenGL and features GLSL shaders, CG shaders, deferred rendering, dynamic shadows, bullet based physics library, terrain engine, skeleton based animation meshes, exporter for Blender, portals, etc...
Cross platform 2D game creation framework with Python bindings
FIFE is a cross platform 2D game creation framework written in C++ with Python bindings. It's designed to be flexible enough to support a wide variety of 2D game types but specializes in 2D isometric type views.
Spring is a versatile 3D RTS game engine. Using extensively Lua for scripting game-specific code to make nearly every aspect of the engine customizable, from GUI, to unit AI, to pathfinding.
Urban Shadow is a real-time RPG based on the classic game, Shadowrun. The game is being developed using the Python programming language and the pyGame library.
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Galclone is a free clone of the simple 2d real-time strategy game galcon. Like his archetype, galclone is written in python and uses the pygame module (LGPL) for its gui.
Era of Mages is a realtime strategy game with many roleplaying aspects to it. It is inspired by Warcraft but provides players with many new and interesting features. The implementation is done with the pygame (Python+SDL) library.
Pysox is an open-source library for the development of isometric, 3D games (RTS and TBS chiefly). It will be scriptable in either Python or Lua. It is written in Objective-C using GNUstep, OpenGL, and SDL.
Basicaly gar3d is a RTS... but you don\'t have control over your smaller units, but you can order your officers with high level commands like fallback and rush. Also this game is a RPG with your officers gaining stats and levels.
Pyplace is a toolkit which helps Python developers to render data as isometrically viewed 'places' around which the user can navigate.
The look and feel by version 1 will be similar to an early UO or AOE, but only a few unit sprites & no network