Unknown Horizons is a 2D realtime strategy simulation with an emphasis on economy and city building. Expand your small settlement to a strong and wealthy colony and supply your inhabitants with valuable goods. LINUX PACKAGES: http://bit.ly/aurIC2
Cross platform 2D game creation framework with Python bindings
FIFE is a cross platform 2D game creation framework written in C++ with Python bindings. It's designed to be flexible enough to support a wide variety of 2D game types but specializes in 2D isometric type views.
Galclone is a free clone of the simple 2d real-time strategy game galcon. Like his archetype, galclone is written in python and uses the pygame module (LGPL) for its gui.
The Unknown Horizon project aims at creating an open source realtime economy simulation game with strategy elements in an isometric 2D engine loosely oriented towards Sunflower's Anno series.
Falconer-Try Studios is developing this new gaming engine for 2D, 3D and soon VR environments. It will be best for RTS and FPS games. See the documentation for more data.
Mix of RPG and Tower defense game. Player leads a small team and explores a huge world of connected floating islands. 2d isometric view and NO acceleration required.