Search Results for "genomics"

Seurat is a comprehensive R toolkit for single-cell genomics analysis, introduced by the Satija Lab at NYGC. It supports quality control, normalization, clustering, integration of multimodal data (e.g., scRNA‑seq, spatial, CITE‑seq), and visualization. Seurat v5 introduces scalable workflows and spatial transcriptomics support, commonly used in academic and industry research for single-cell studies.

...It is part of a larger ecosystem: the compiled HTML / book version of the labs is published via a companion “book” repository, which presents a polished, browsable version of the materials. The content covers topics such as data wrangling in R, statistical inference, genomics workflows, Bioconductor packages, and project-based analyses. Because it’s open and modular, contributors can suggest improvements, update modules, or add new exercises.

ComplexHeatmap is an R/Bioconductor package by Zuguang Gu et al. designed to create highly flexible, complex, richly annotated heatmaps and related visualizations. It allows arranging multiple heatmaps, adding annotations, combining heatmaps, customizing colors, layouts, and integrating other plots. Often used in genomics/bioinformatics to show expression, methylation, etc., with sidebars, annotations, clustering, etc. Highly customizable layout: combining different heatmaps, arranging and splitting, dealing with multiple heatmap merges, combining with other plots etc. Integration with Shiny / interactive heatmaps via companion packages (InteractiveComplexHeatmap) to allow interactivity, etc.

...It implements many types of plots using circular layouts: chord diagrams, circular heatmaps, arcs/links between sectors, genomic data visualization, etc. It provides low-level drawing functions as well as high-level functions to build complex visualizations. It’s often used in genomics, network analysis, or other fields where relationships among categories or entities can be nicely displayed in a circular fashion. Support for circular heatmaps, multiple tracks (rings), for showing multiple layers of data per sector. Good performance and stable codebase, detailed documentation including a book on usage examples.