Diggo a 2D version of minecraft made with Pygame!
Develop an emulated Darkfall Online Server.
A ridiculously simple spaceship shoot 'em up game written in Python
A text-based adaptation of the classic tabletop game 'Pass the Pigs'
Pygrid is an open-source and cross-platform pygame/python 2D engine.
CometZ is a simple side scrolling space shooter
Super Mario Python Final
A 2D Elite-style game written in Python 3.2.
Python/Pygame Game-Building Framework
Cross platform 2D game creation framework with Python bindings
Tactical, turn-based game engine, that uses OpenGL and WinAPI
Open source, moddable game engine for the "Polygon Love 2" game
Access to Irrlicht Engine SDK from assembler, C, Python, Basic, Pascal
Open Source Virtual World and MMOG Development Platform
2d vector space combat game inspired by space war
2D Multi-directional Shooter
Invaders like game, written in Python with Curses... :)
nctdtool, a curses front-end for tdtool
rp6simul is a simulator for the RP6 robot (AREXX Engineering)