Open Source Python Software - Page 22

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Browse free open source Python Software and projects below. Use the toggles on the left to filter open source Python Software by OS, license, language, programming language, and project status.

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  • 1
    labelme Image Polygonal Annotation

    labelme Image Polygonal Annotation

    Image polygonal annotation with Python

    Labelme is a graphical image annotation tool. It is written in Python and uses Qt for its graphical interface. Image annotation for polygon, rectangle, circle, line and point. Image flag annotation for classification and cleaning. Video annotation. (video annotation). GUI customization (predefined labels / flags, auto-saving, label validation, etc). Exporting VOC-format dataset for semantic/instance segmentation. (semantic segmentation, instance segmentation). Exporting COCO-format dataset for instance segmentation. (instance segmentation). The first time you run labelme, it will create a config file in ~/.labelmerc. You can edit this file and the changes will be applied the next time that you launch labelme. If you would prefer to use a config file from another location, you can specify this file with the --config flag.
    Downloads: 13 This Week
    Last Update:
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  • 2
    notebooklm-py

    notebooklm-py

    Unofficial Python API and agentic skill for Google NotebookLM

    notebooklm-py is an unofficial Python API and agent-ready integration layer for Google NotebookLM that exposes NotebookLM functionality through code, the command line, and AI agent workflows. Its goal is to provide programmatic access not just to standard notebook operations, but also to many capabilities that are either limited or unavailable in the web interface, making it especially useful for automation and custom pipelines. The project covers notebook management, source ingestion, conversational querying, research workflows, and sharing controls, while also enabling the generation of a wide range of study and media artifacts. These outputs include audio overviews, videos, slide decks, infographics, quizzes, flashcards, reports, data tables, and mind maps, with configurable formats and export options.
    Downloads: 13 This Week
    Last Update:
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  • 3
    plotly.py

    plotly.py

    The interactive graphing library for Python

    plotly.py is a browser-based, open source graphing library for Python that lets you create beautiful, interactive, publication-quality graphs. Built on top of plotly.js, it is a high-level, declarative charting library that ships with more than 30 chart types. Everything from statistical charts and scientific charts, through to maps, 3D graphs and animations, plotly.py lets you create them all. Graphs made with plotly.py can be viewed in Jupyter notebooks, standalone HTML files, or hosted online using Chart Studio Cloud.
    Downloads: 13 This Week
    Last Update:
    See Project
  • 4
    py-kms

    py-kms

    KMS Server Emulator written in Python

    py-kms is a Python-based emulator of Microsoft’s Key Management Service (KMS), designed to simulate activation servers for Windows and Microsoft Office volume licensing systems. It is derived from earlier implementations and reverse-engineered protocols, allowing it to respond to activation requests from client machines. The software supports multiple versions of the KMS protocol, enabling compatibility with a wide range of Windows and Office releases. It can be deployed in various environments, including standalone systems, Docker containers, and service managers like systemd, making it flexible for testing and development scenarios. The emulator includes features such as logging, configurable network parameters, and persistent storage using SQLite. While it is often used for testing activation workflows, it also serves as a practical example of protocol emulation and reverse engineering in software systems.
    Downloads: 13 This Week
    Last Update:
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    Streamline Azure Security with Palo Alto Networks VM-Series

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  • 5
    scikit-learn

    scikit-learn

    Machine learning in Python

    scikit-learn is an open source Python module for machine learning built on NumPy, SciPy and matplotlib. It offers simple and efficient tools for predictive data analysis and is reusable in various contexts.
    Downloads: 13 This Week
    Last Update:
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  • 6
    sqlmap

    sqlmap

    Automatic SQL injection and database takeover tool

    sqlmap is a powerful, feature-filled, open source penetration testing tool. It makes detecting and exploiting SQL injection flaws and taking over the database servers an automated process. sqlmap comes with a great range of features that along with its powerful detection engine make it the ultimate penetration tester. It offers full support for MySQL, Oracle, PostgreSQL, Microsoft SQL Server, Microsoft Access, IBM DB2, SQLite, Firebird, and many other database management systems. It also comes with a wide set of switches which include database fingerprinting, over data fetching from the database, accessing the underlying file system, and more.
    Downloads: 13 This Week
    Last Update:
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  • 7
    Métamorphose File and Folder Renamer
    A cross platform file and folder mass renamer, allows many different renaming operations in a GUI. Please note that development has moved to GitHub: https://github.com/metamorphose
    Downloads: 81 This Week
    Last Update:
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  • 8
    KoboldCpp

    KoboldCpp

    Run GGUF models easily with a UI or API. One File. Zero Install.

    KoboldCpp is an easy-to-use AI text-generation software for GGML and GGUF models, inspired by the original KoboldAI. It's a single self-contained distributable that builds off llama.cpp and adds many additional powerful features.
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    Downloads: 340 This Week
    Last Update:
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  • 9
    ADB Sync

    ADB Sync

    Synchronize files between a PC and Android device using ADB

    adb-sync is a command-line utility designed to synchronize files between a PC and an Android device over the Android Debug Bridge (ADB). It simplifies the process of transferring and mirroring directories without requiring root access or complex configuration. By comparing file states between the host and the device, adb-sync efficiently updates only changed files, reducing transfer time and bandwidth usage. The tool also supports reverse synchronization, allowing users to copy data from an Android device back to their PC. While this project has been deprecated in favor of better-adb-sync, it remains a lightweight and effective option for managing file transfers and backups over USB debugging connections.
    Downloads: 12 This Week
    Last Update:
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  • 10
    AI Runner

    AI Runner

    Offline inference engine for art, real-time voice conversations

    AI Runner is an offline inference engine designed to run a collection of AI workloads on your own machine, including image generation for art, real-time voice conversations, LLM-powered chatbots and automated workflows. It is implemented as a desktop-oriented Python application and emphasizes privacy and self-hosting, allowing users to work with text-to-speech, speech-to-text, text-to-image and multimodal models without sending data to external services. At the core of its LLM stack is a mode-based architecture with specialized “modes” such as Author, Code, Research, QA and General, and a workflow manager that automatically routes user requests to the right agent based on the task. The project has a strong focus on developer ergonomics, with thorough development guidelines, environment configuration using .env variables, and a clear structure for tests, tools and agents.
    Downloads: 12 This Week
    Last Update:
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  • 11
    AIOGram

    AIOGram

    Framework for Telegram Bot API written in Python 3.7 with asyncio

    aiogram is modern and fully asynchronous framework for Telegram Bot API written in Python with asyncio and aiohttp. It helps you to make your bots faster and simpler. Is a pretty simple and fully asynchronous framework for Telegram Bot API written in Python 3.7 with asyncio and aiohttp.
    Downloads: 12 This Week
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  • 12
    AlphaFold 3

    AlphaFold 3

    AlphaFold 3 inference pipeline

    AlphaFold 3, developed by Google DeepMind, is an advanced deep learning system for predicting biomolecular structures and interactions with exceptional accuracy. This repository provides the complete inference pipeline for running AlphaFold 3, though access to the model parameters is restricted and must be obtained directly from Google under specific terms of use. The system is designed for scientific research applications in structural biology, biochemistry, and bioinformatics, enabling accurate modeling of proteins, ligands, and covalent modifications. Users can perform local predictions via Docker containers, integrating AlphaFold 3’s inference process with provided JSON input configurations. The software includes flexible options for running both data preprocessing and GPU-accelerated inference, allowing users to adapt to available computational resources.
    Downloads: 12 This Week
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  • 13
    Antigravity Awesome Skills

    Antigravity Awesome Skills

    The Ultimate Collection of 700+ Agentic Skills for Claude Code

    Antigravity Awesome Skills is a playful yet practical repository that curates a set of clever, expressive, and sometimes whimsical AI agent skill templates designed to help users bootstrap agent behavior quickly. Rather than focusing on production-grade systems, it provides creative and high-impact skills that demonstrate how agents can be used to automate tasks, generate content, assist with daily operations, or integrate into larger workflows with minimal configuration. The project includes skill definitions, example prompts, and usage patterns that highlight how modular abilities can be assembled into functioning assistants. Because it aims to reduce cognitive overhead, many skills show how to structure intents, handle context, and orchestrate multi-step reasoning without deep technical complexity. It also serves as inspiration for users looking to prototype new use cases — from conversational helpers that answer questions to workflow automators that trigger actions.
    Downloads: 12 This Week
    Last Update:
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  • 14
    AutoGPT

    AutoGPT

    Powerful tool that lets you create and run intelligent agents

    AutoGPT is an experimental open-source application showcasing the capabilities of the GPT-4 language model. This program, driven by GPT-4, chains together LLM "thoughts", to autonomously achieve whatever goal you set. As one of the first examples of GPT-4 running fully autonomously, AutoGPT pushes the boundaries of what is possible with AI.
    Downloads: 12 This Week
    Last Update:
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  • 15
    BackgroundRemover

    BackgroundRemover

    Background Remover lets you Remove Background from images and video

    BackgroundRemover is a command line tool to remove background from image and video, made by nadermx to power BackgroundRemoverAI. If you wonder why it was made read this short blog post.
    Downloads: 12 This Week
    Last Update:
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  • 16
    Buster

    Buster

    OSINT tool for discovering information linked to email addresses

    Buster is an open source OSINT tool designed for email reconnaissance and information gathering. It helps investigators, security researchers, and penetration testers discover publicly available information related to email addresses and usernames. It can analyze an email address to identify associated social media accounts, references across the web, and potential data breaches linked to that email. It also performs reverse WHOIS lookups to discover domains that may have been registered using a specific email address. In addition to investigating existing addresses, Buster can generate possible email combinations and usernames based on personal details such as a person’s name, birthdate, or additional hints. Buster supports validating generated email addresses and retrieving contextual information about them. By combining multiple online sources and services, Buster helps automate the process of gathering intelligence related to digital identities.
    Downloads: 12 This Week
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  • 17
    Cozette

    Cozette

    A bitmap programming font optimized for coziness

    A bitmap programming font optimized for coziness. Cozette is a 6x13px (bounding box; average 5px character width, 3px descent, 10px ascent, 8px cap height) bitmap font based on Dina, which itself is based on Proggy. It's also heavily inspired by Creep. I absolutely adore Creep, and was using it up until I got a higher-DPI screen for which it was slightly too small. That prompted me to make the bitmap font I always wished existed: Cozette; a small-but-not-tiny bitmap font with great coverage of all the glyphs you might encounter in the terminal. I'm intentionally putting the emphasis on "you" - although Cozette already has all the glyphs I've seen in my CLI tools so far, you might find it's missing a glyph you wish it had. If that's the case, please file an issue! It's an important goal for Cozette to be a useful bitmap alternative to Nerd Fonts. Bitmap fonts are, effectively, just that - bitmaps.
    Downloads: 12 This Week
    Last Update:
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  • 18
    Fixed drivers for Wacom Bamboo

    Fixed drivers for Wacom Bamboo

    Fixes the Wacom Bamboo, Graphire, Intuos 1+2+3 and Cintiq 1st gen

    Wacom's macOS drivers for Bamboo, Graphire, Intuos 1, 2 & 3 and Cintiq 1st gen tablets have bugs in them that cause them to completely fail to start on macOS 10.15 Catalina and later versions (including 11 Big Sur and 12 Monterey). This doesn't apply to the Windows driver, or to the drivers for their newer tablets. When you try to open the Wacom preference pane with a Bamboo tablet, you'll get an error message saying "Waiting for synchronization", then finally "There is a problem with your tablet driver. Please reboot your system. If the problem persists reinstall or update the driver". For an Intuos 3 or Cintiq 1st gen tablet, the preference pane will open, but clicking anything will cause it to crash with the message "There was an error in Wacom Tablet preferences." For Graphire and Intuos 1 & 2 tablets, the driver's installer couldn't even run on Catalina.
    Downloads: 12 This Week
    Last Update:
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  • 19
    Frappe

    Frappe

    Low code web framework for real world applications

    Frappe is a full-stack, low-code web framework written in Python and JavaScript, used to build scalable and modular enterprise applications. It powers ERPNext and includes tools for REST APIs, user management, document modeling, workflows, and real-time updates. Frappe uses a "model-view-controller" approach with its own ORM and frontend system, enabling rapid development without sacrificing control or performance.
    Downloads: 12 This Week
    Last Update:
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  • 20
    Goose Developer Agent

    Goose Developer Agent

    Goose is a developer agent that operates from your command line

    Goose is a developer agent that supercharges your software development by automating an array of coding tasks directly within your terminal or IDE. Guided by you, it can intelligently assess your project's needs, generate the required code or modifications, and implement these changes on its own. Goose can interact with a multitude of tools via external APIs such as Jira, GitHub, Slack, infrastructure and data pipelines, and more -- if your task uses a shell command or can be carried out by a Python script, Goose can do it for you too! Like semi-autonomous driving, Goose handles the heavy lifting, allowing you to focus on other priorities. Simply set it on a task and return later to find it completed, boosting your productivity with less manual effort.
    Downloads: 12 This Week
    Last Update:
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  • 21
    Gradio

    Gradio

    Create UIs for your machine learning model in Python in 3 minutes

    Gradio is the fastest way to demo your machine learning model with a friendly web interface so that anyone can use it, anywhere! Gradio can be installed with pip. Creating a Gradio interface only requires adding a couple lines of code to your project. You can choose from a variety of interface types to interface your function. Gradio can be embedded in Python notebooks or presented as a webpage. A Gradio interface can automatically generate a public link you can share with colleagues that lets them interact with the model on your computer remotely from their own devices. Once you've created an interface, you can permanently host it on Hugging Face. Hugging Face Spaces will host the interface on its servers and provide you with a link you can share. One of the best ways to share your machine learning model, API, or data science workflow with others is to create an interactive demo that allows your users or colleagues to try out the demo in their browsers.
    Downloads: 12 This Week
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  • 22
    HexStrike AI MCP Agents

    HexStrike AI MCP Agents

    HexStrike AI MCP Agents is an advanced MCP server

    HexStrike AI is an MCP server that lets LLM agents autonomously operate a large catalog of offensive-security tools. Its goal is to bridge “language models” and practical pentest workflows—enumeration, exploitation, vulnerability discovery, and bug bounty reconnaissance—under safe, auditable controls. The server exposes typed tools and guardrails so agent prompts translate to concrete, parameterized actions rather than brittle shell strings. It ships with curated tool adapters, task orchestration, and guidance for connecting popular agent clients (Claude, GPT, Copilot) to a hardened execution environment. Documentation highlights the breadth of supported utilities and positions HexStrike as a research and red-team aid, not a point-and-click exploit kit. A public site and active repository activity signal an expanding community around autonomous security research agents.
    Downloads: 12 This Week
    Last Update:
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  • 23
    Hindsight

    Hindsight

    Hindsight: Agent Memory That Learns

    Hindsight is an advanced, open-source memory system for AI agents designed to enable long-term learning, reasoning, and consistency across interactions by treating memory as a first-class component of intelligence rather than a simple retrieval layer. It addresses one of the core limitations of modern AI agents, which is their inability to retain and meaningfully use past experiences over time, by introducing a structured, biomimetic memory architecture inspired by how human memory works. Instead of relying solely on vector similarity or basic retrieval techniques, Hindsight organizes information into distinct categories such as facts, experiences, beliefs, and observations, allowing agents to differentiate between raw data and inferred knowledge. The system operates through three core mechanisms—retain, recall, and reflect—which respectively handle storing information, retrieving relevant context, and generating new insights based on accumulated experience.
    Downloads: 12 This Week
    Last Update:
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  • 24
    Lemonade

    Lemonade

    Lemonade helps users run local LLMs with the highest performance

    Lemonade is a local LLM runtime that aims to deliver the highest possible performance on your own hardware by auto-configuring state-of-the-art inference engines for both NPUs and GPUs. The project positions itself as a “local LLM server” you can run on laptops and workstations, abstracting away backend differences while giving you a single place to serve and manage models. Its README emphasizes real-world adoption across startups, research groups, and large companies, signaling a focus on practical deployments rather than toy demos. The repository highlights easy onboarding with downloads, docs, and a Discord for support, suggesting an active user community. Messaging centers on squeezing maximum throughput/latency from modern accelerators without users having to hand-tune kernels or flags. Releases further reinforce the “server” framing, pointing developers toward a service that can be integrated into apps and tools.
    Downloads: 12 This Week
    Last Update:
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  • 25
    Miso TTS

    Miso TTS

    Miso TTS is an 8 billion, highly emotive text-to-speech model

    Miso TTS is an advanced 8-billion-parameter text-to-speech model developed by Miso Labs for generating highly expressive and natural-sounding conversational speech. Built on an RVQ Transformer architecture inspired by Sesame CSM, it combines a powerful Llama-based backbone with an autoregressive audio decoder to produce high-quality audio from text. The model supports both standard speech synthesis and voice-conditioned generation using optional audio prompts for voice cloning. Miso TTS generates Mimi audio codes and can leverage conversation history to create more contextually aware and realistic dialogue. Designed for local deployment, it offers watermarking by default to help promote responsible use of generated audio. With its focus on emotive speech generation, Miso TTS delivers state-of-the-art performance for AI voice applications, virtual assistants, and conversational AI experiences.
    Downloads: 12 This Week
    Last Update:
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