Human protein similarity network used to predict drug safety.
This is the protein similarity network - PSIN. Here, the nodes are human proteins and they are linked only if they share considerable sequence similarity.
We found that this network is particularly useful to distinguish approved from problematic drug-targets.
Here you also find the complete set of programs and datasets we used for this purpose.
Free to help further test and develop this project. Your help and expertise are much appreciated !
If you have any questions, please do...
A pipeline for quantitative proteomics based upon isobaric tags
...This website contains the IQuant software, an example data labeled by iTRAQ-8plex for testing and a user's manual. If you have any question about IQuant, please contact me: wenbo@genomics.cn.
The sourcecode of IQuant can be found here "https://sourceforge.net/p/iquant/code/".