Showing 352 open source projects for "dna"

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    Discourse Network Analyzer (DNA)

    Discourse Network Analyzer (DNA)

    Discourse Network Analyzer (DNA)

    The Java software Discourse Network Analyzer (DNA) is a qualitative content analysis tool with network export facilities. You import text files and annotate statements that persons or organizations make, and the program will return network matrices of actors connected by shared concepts.
    Downloads: 1 This Week
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  • 2
    pydna

    pydna

    Clone with Python! Data structures for double stranded DNA

    Clone with Python! Data structures for double stranded DNA & simulation of homologous recombination, Gibson assembly, cut & paste cloning. Planning genetic constructs with many parts and assembly steps, such as recombinant metabolic pathways, are often difficult to properly document as is evident from the poor state of documentation in the scientific literature. The pydna python package provide a human-readable formal description of cloning and genetic assembly strategies in Python which allow for simulation and verification. ...
    Downloads: 0 This Week
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  • 3
    Evo 2

    Evo 2

    Genome modeling and design across all domains of life

    Evo 2 is a DNA language model system designed for long-context genome modeling and biological sequence design across all domains of life. The project models DNA at single-nucleotide resolution and supports context windows of up to one million base pairs, which places it in a class of models built for very large genomic reasoning tasks. According to the repository, it uses the StripedHyena 2 architecture, was pretrained with Savanna, and was trained autoregressively on the OpenGenome2 dataset containing 8.8 trillion tokens. ...
    Downloads: 5 This Week
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  • 4
    AlphaGenome

    AlphaGenome

    Programmatic access to the AlphaGenome model

    The AlphaGenome API provides access to AlphaGenome, Google DeepMind’s unifying model for deciphering the regulatory code within DNA sequences. This repository contains client-side code, examples, and documentation to help you use the AlphaGenome API. AlphaGenome offers multimodal predictions, encompassing diverse functional outputs such as gene expression, splicing patterns, chromatin features, and contact maps. The model analyzes DNA sequences of up to 1 million base pairs in length and can deliver predictions at single-base-pair resolution for most outputs. ...
    Downloads: 1 This Week
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    Bowtie 2

    Bowtie 2

    A fast and sensitive gapped read aligner

    ...Bowtie 2 outputs alignments in SAM format and includes companion utilities for building and inspecting indexes. It is widely used in bioinformatics pipelines for RNA-seq, DNA-seq, metagenomics, variant analysis, and other sequencing-based research tasks. Overall, Bowtie 2 remains a foundational command-line tool for high-throughput sequence alignment and reproducible computational biology workflows.
    Downloads: 50 This Week
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  • 6
    nuwa-skill

    nuwa-skill

    Mental models, decision heuristics, expressing DNA

    nuwa-skill is an AI-oriented project focused on defining, managing, and executing modular “skills” that can be used by intelligent agents or automation systems. It provides a framework for organizing capabilities into reusable units that can be invoked dynamically depending on context or user input. The project is designed to integrate with AI systems, enabling them to perform structured tasks such as data retrieval, processing, or interaction with external services. It emphasizes modularity...
    Downloads: 5 This Week
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  • 7
    Marin

    Marin

    Framework for research and development of foundation models

    ...Experiments and decisions are documented as they occur, including unsuccessful approaches. The framework is primarily used for large language models but has also supported audio-text, DNA, and protein modeling research. Experiments are expressed as dependent steps that execute in topological order, enabling reproducible training workflows. Marin also provides model checkpoints, training recipes, scaling research, documentation, and reusable infrastructure for large-scale experiments.
    Downloads: 0 This Week
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  • 8
    ESPResSo

    ESPResSo

    The ESPResSo package

    ...It is designed for coarse-grained and bead-spring models used in physics, chemistry, and molecular biology. The software can model systems such as polymers, colloids, liquid crystals, ferrofluids, DNA, lipid membranes, and other complex fluids. It includes a broad range of interaction potentials and algorithms for electrostatics, hydrodynamics, and coupled particle-field behavior. ESPResSo is controlled through Python, which makes it flexible for custom simulation setup and analysis. Its main value is giving soft matter researchers a versatile and extensible platform for studying many-particle systems beyond simple atomistic models.
    Downloads: 0 This Week
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  • 9
    AWS ParallelCluster Cookbook

    AWS ParallelCluster Cookbook

    The Chef cookbook used to build and bootstrap AWS ParallelCluster

    ...AWS ParallelCluster facilitates both quick start proof of concepts (POCs) and production deployments. You can build higher-level workflows, such as a Genomics portal that automates the entire DNA sequencing workflow, on top of AWS ParallelCluster. Node.js is required by AWS CDK library used by ParallelCluster.
    Downloads: 0 This Week
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    AWS ParallelCluster Node

    AWS ParallelCluster Node

    Python package installed on the Amazon EC2 instances

    ...AWS ParallelCluster facilitates both quick start proof of concepts (POCs) and production deployments. You can build higher-level workflows, such as a Genomics portal that automates the entire DNA sequencing workflow, on top of AWS ParallelCluster.
    Downloads: 0 This Week
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  • 11
    Bowtie, an ultrafast, memory-efficient short read aligner for short DNA sequences (reads) from next-gen sequencers. Please cite: Langmead B, et al. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol 10:R25.
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    Downloads: 487 This Week
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  • 12

    CpGtools

    Python package to analyze DNA methylation data

    CpGtools package provides a number of Python programs to annotate, QC, visualize, and analyze DNA methylation data generated from Illumina HumanMethylation450 BeadChip (450K) / MethylationEPIC BeadChip (850K) array or RRBS / WGBS.
    Downloads: 0 This Week
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  • 13

    proSeq

    ProSeq is a GUI program to edit and analyse DNA polymorphism datasets

    ProSeq ('Processor of sequences') is a package including GUI and command line programs to process and analyse DNA polymorphism data. It allows one to open and save sequence data in over a dozen file formats (and convert between these formats). It shows sequence alignments in a graphical window and allows the user to edit, manipulate and analyse sequences in various ways. ProSeq4 includes tools to analyse DNA polymorphism, scan for selection, do PCA and reconstruct phylogenies from sequence or SNP data. ...
    Downloads: 1 This Week
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  • 14
    oxDNA

    oxDNA

    A code primarily aimed at DNA and RNA coarse-grained simulations

    The oxDNA code has been moved to https://github.com/lorenzo-rovigatti/oxDNA, please go there for new releases.
    Downloads: 10 This Week
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  • 15
    hg38 version of the pipelines for whole exome sequencing: exome_test38.sh wole transcription sequencing: rna_test38.sh somatic calling: somatic38.sh SV detect: svdetect38.sh, meerkat38.sh cnv: svdetectcnv38.sh, contra38.sh, cnvkit38.sh *** Mutect2 instead of haptotypecaller is used to call variants in DNA-seq.
    Downloads: 2 This Week
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  • 16

    MEDe-KIT

    Micro Educational and Development Kit (MEDe-KIT)

    Micro Educational and Development Kit (MEDe-KIT) is an educational software for storing and viewing information about study material information uploaded to it like images and text descriptions. It uses ODBC for storing uploaded data into local database. Its features also include a genes sequencer for generating combination of DNA and RNA sequence entered. Thanks and hope this is useful for everyone who are interested in science and learning. The project was developed using NetBeans IDE and Java. Default login user name : user Default login password : user
    Downloads: 0 This Week
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  • 17

    janda

    structural variant detector

    Janda is a tool to detect structural variants in whole-genome DNA sequence data. It identifies structural variants (deletions, duplications, translocations, and inversions) using anomalously mapped pair reads and realigning potential junction reads.
    Downloads: 0 This Week
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  • 18
    relax

    relax

    Molecular dynamics by NMR data analysis

    The software package 'relax' is designed for the study of molecular dynamics through the analysis of experimental NMR data. Organic molecules, proteins, RNA, DNA, sugars, and other biomolecules are all supported. It supports exponential curve fitting for the calculation of the R1 and R2 relaxation rates, calculation of the NOE, reduced spectral density mapping, the Lipari and Szabo model-free analysis, study of domain motions via the N-state model and frame order dynamics theories using anisotropic NMR parameters such as RDCs and PCSs, the investigation of stereochemistry in dynamic ensembles, and the analysis of relaxation dispersion data.
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    Downloads: 8 This Week
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  • 19

    ParDRe

    Parallel tool to remove duplicate DNA reads

    ParDRe is a parallel tool to remove duplicate reads. Duplicate reads can be seen as identical or nearly identical sequences with some mismatches. This tool will let the users to avoid the analysis of not necessary reads, reducing the time of subsequent procedures with the dataset (e.g., assemblies, mappings, etc.). The tool is implemented with MPI in order to exploit the parallel capabilities of multicore clusters. It is faster than multithreaded counterparts (end of 2015) for the same...
    Downloads: 1 This Week
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  • 20
    RedDiamond

    RedDiamond

    Text editor supporting EDT keypad navigation

    This began as a fork of the Diamond text editor. It now shares very little DNA with Diamond because it uses CsScintilla edit widgets and has many more features. EDT keypad navigation, themes, configurable backup history, along with many other improvements have happened. Project still uses CopperSpice cross platform library. Linux users upgrading from older versions to 3.5.8 or later should cd .local/share rm -rf LogikalSolutions rm -rf LogikalSolutions-RedDiamond/ rm -rf ~/.config/LogikalSolutions-RedDiamond/ Due to database changes.
    Downloads: 0 This Week
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  • 21
    MAF

    MAF

    Bash Framework to combine many preprocessing and alignment tools

    DNA and RNA nucleotide sequences are an ubiquitous element of all biological cells and are serving on one hand as a comprehensive library of capabilities for the cells and on the other as an impressive regulatory system to control cellular function. The presented multi-alignment framework (MAF) should give researchers a simple sequence alignment platform as a functional template, flexible enough to adjust all steps but also comprehensive enough to join many different tools and custom parameter combinations if in-depth analysis is necessary or advised in e.g. low read rate situations. ...
    Downloads: 0 This Week
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  • 22
    Gemi

    Gemi

    PCR primers / probes design from multiple & degenerate sequences

    Gemi, an automated, fast, and easy-to-use bioinformatics tool with a user-friendly interface to design primers and probes for polymerase chain reaction (PCR). Gemi accepts multiple aligned and long DNA and RNA sequences with degenerate nucleotide (non-A/C/G/T bases). Gemi can be used for quantitative, real-time and conventional PCR (qPCR, rt-PCR, etc.), and Sanger sequencing. Gemi can parse large dataset of sequences efficiently. Python source code is available upon request. Milestone: The tool reached about 3000 downloads sine 2012. ...
    Downloads: 1 This Week
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  • 23
    gendasm

    gendasm

    Generic Code-Seeking Diassembler with Fuzzy-Function Analyzer

    ...It allows you to enter known starting vectors for a given code image for the micro. It will disassemble the code and follow through branches to assist in the separation of code and data. Its included Fuzzy Function Analyzer companion uses a DNA Sequence Alignment Algorithm to locate similar code in multiple binaries to facilitate reverse-engineering and/or code recovery. The original purpose of the Fuzzy Function Analyzer was to assist in code recovery where the source code for the current binaries got lost, yet the source code for an old binary was retained. The Fuzzy Function Analyzer allows you to match up known functions between the two binaries so you can concentrate on disassembling and reverse engineering the parts that are different and recover the code for the current binary that got lost.
    Downloads: 0 This Week
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  • 24
    Gel Blot Analyzer is a comprehensive desktop application designed to streamline the annotation, analysis, and presentation of gel electrophoresis images. Built for researchers, students, and scientists, this tool simplifies the often tedious process of preparing gel images (SDS-PAGE, Western Blots, DNA gels, etc.) for lab notebooks, presentations, and publications. From precise labeling and molecular weight prediction to powerful densitometric analysis, Gel Blot Analyzer combines essential imaging tools into a single, intuitive workflow. Since this application is not signed on Windows first run, please click on Run Anyway after uncompressing. ...
    Downloads: 1 This Week
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  • 25
    NGSEP

    NGSEP

    NGSEP (Next Generation Sequencing Experience Platform)

    NGSEP is an integrated framework for analysis of short and long DNA high throughput sequencing reads. The current version provides functionalities for both de-novo and reference guided analysis of sequencing data, including genome assembly, read mapping, variants detection and genotyping and de-novo analysis of data generated from reduced representation protocols. NGSEP also provides modules for analysis of genomic variation databases (VCF files), including functional annotation, filtering, format conversion, comparison, clustering, imputation, introgression analysis and different kinds of statistics. ...
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    Downloads: 0 This Week
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