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A HMM-based algorithm for defining enriched regions from ChIP-seq data
...Testing on real data shows that these regions are indeed highly enriched by the right protein binding sites.
Command (single-end):
perl /compbio/software/HPeak3/HPeak.pl -sp HUMAN/MOUSE -format BED -t TREATMENT.inp -c CONTROL.inp -n OUTPUTPREFIX -fmin 100 -fmax 300 -r 36 -ann -wig -seq -interfiles
Command (pair-end):
perl /compbio/software/HPeak3/HPeak.pl -sp HUMAN/MOUSE -format BED -pe TREATMENT.inp -c CONTROL.inp -n OUTPUTPREFIX -isize 200 -r 100 -pec (if control is PE) -ann -wig -seq –interfiles
note:
1. Default species is HUMAN. ...