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...Its ByteBuf abstractions, buffer pooling, and zero-copy techniques help reduce GC pressure and improve throughput under heavy I/O. Support for common protocols—HTTP/1.1, HTTP/2, WebSocket, and raw TCP/UDP—makes it a foundation for RPC frameworks, proxies, and messaging systems. Pluggable transports and native integrations (like epoll or kqueue where available) allow fine-tuning for different operating systems. With robust resource management, leak detection, and extensive testing, Netty is widely chosen when low latency, scalability, and control over the I/O stack are required.

Grassroots DiCoM is a C++ library for DICOM medical files. It is accessible from Python, C#, Java and PHP. It supports RAW, JPEG, JPEG 2000, JPEG-LS, RLE and deflated transfer syntax. It comes with a super fast scanner implementation to quickly scan hundreds of DICOM files. It supports SCU network operations (C-ECHO, C-FIND, C-STORE, C-MOVE). PS 3.3 & 3.6 are distributed as XML files. It also provides PS 3.15 certificates and password based mecanism to anonymize and de-identify DICOM datasets.