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King Phisher is an open source tool that can simulate real world phishing attacks. It has an easy-to-use, flexible architecture that allows for full control over both emails and server content. It is useful for running awareness campaigns and training, and can only be used for legal applications when the explicit permission of the targeted organization has been obtained.
Konfidi is a trust framework that uses topical trust values from a social network of authenticated people. When you receive an email from someone you do not know, but he/she is in the network, Konfidi will compute an inferred trust value for you.
Quotient is multi-protocol (SMTP, POP, IMAP, SIP, HTTP, Q2Q) server that helps with all your online conversations be they over email, IRC, IM, mailing lists or voice over IP. It is written in Python on the Twisted framework and uses Lupy and SpamBayes.
MailBoxer is a framework for building mailinglist-based applications with ZOPE. Out of the box MailBoxer provides mailinglist-, newsletter- and mailarchive-services for ZOPE.