gpsim is an open sourced simulator for Microchip's PIC microcontrollers. It supports all three families of PICs: 12-bit, 14-bit, and 16-bit cores. See also gputils http://gputils.sourceforge.net/
Electronic circuit simulator.
Simple environment to run and debug firmware for AVR 8-bit microprocessors.
Able to run arduino firmware.
Internally this program uses the open source Simavr AVR Processor Simulator (https://github.com/buserror/simavr) and wraps all its functions in a GUI shell. Setups for firmware debugging scenarios can be created dynamically.
A multi-ISA "assembly debugger" with graphical and terminal frontends. Currently sporting LC-3, Georgia Tech's LC-2200, and brain*. MIPS support is in the making, to compete with SPIM. (Windows, Linux, MacOSX; LC-3 simulator and LC-2200 simulator)
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Microdev is a complete development tool dedicated to microcontroller based boards. It is composed of a graphical and real time simulator and a full featured editor supporting Picbasic, JAL and Asm.
VirtuAL3101 provides a series of tools to develop effects using the AL3101 DSP from Alesis. It includes an assembler/disassembler, a simulator, an application generator with its graphical interface and various effects.
NEmu is an emulator/simulator for exploring computer architecture. It
provides a virtual machine, a debugger, and simulations of various cpus
and hardware. NEmu is built on top of ALib, my own application framework.
GNUDE is a complete suite of GNU C, C++, Fortran, and Java Cross Compilers, and the GDB CPU Simulator and Debugger for embedded microprocessor applications development. Targets development for ARM7, ARM9, and XScale applications.