DNAA is the DNA analysis package, for analyzing next-generation post-alignment whole genome resequencing data. Specifically, DNAA is able to find structural variation, SNP and indel variants, as well as evaluating the mapping and data quality.
Parse, analyze and -- most importantly -- use COBOL data definitions. This gives you access to COBOL data from Python programs. Write data analyzers, one-time data conversion utilities and Python programs that are part of COBOL systems. Really.