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...Accordingly, CCO classes and relations are heavily constrained by the BFO framework, from which it inherits much of its basic semantic relationships.
An optimization toolbox for probabilistic Boolean networks
We introduce optPBN, a Matlab-based toolbox for the optimization of probabilistic Boolean networks (PBN) which operates under the framework of the BN/PBN toolbox from Shmulevich et al. optPBN offers an easy generation of probabilistic Boolean networks from Boolean rule-based modeling and allows for flexible measurement data integration from multiple experiments and a subsequent integrated optimization problem generation which then can be solved with different optimizers. Thereby optPBN...