Showing 40 open source projects for "gene"

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  • 1
    MCScanX

    MCScanX

    MCScanX: Multiple Collinearity Scan toolkit X version

    MCScanX is a toolkit for detecting gene synteny and collinearity, aiding in the evolutionary analysis of gene arrangements across multiple genomes. It extends the original MCScan algorithm by incorporating additional utilities for visualization and downstream analyses.
    Downloads: 0 This Week
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  • 2

    MPIGeneNet

    Parallel tool to construct gene co-expression networks

    MPIGeneNet is a parallel tool to construct gene co-expression networks using Pearson’s correlation and Random Matrix Theory (RMT). This tool takes as input a matrix with the expression values (a float value) for different genes observed from several samples. It is a parallelization of RMTGenNet tool (https://github.com/spficklin/RMTGeneNet). MPIGeneNet integrates the whole procedure of creating the in one program, which makes the tool easier to work with (the users only have to launch the application once) and avoids writing/reading from intermediate files among the modules.
    Downloads: 0 This Week
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  • 3

    miRPV

    miRPV: An automated pipeline for miRNA Prediction and Validation in si

    miRPV is an Automated tool that allows users to predict and validate microRNA from genome/gene sequence. System Requirement CPU: AMD64 (64bit) Memory: 2Gb RAM Storage: 5Gb Ubuntu 18.04
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  • 4
    Fun4Me

    Fun4Me

    A package for functional annotation for metagenomes

    This package includes a few programs for rapid functional annotation for metagenomic sequences, including, 1) Gene prediction by FragGeneScan; 2) Similarity search by RAPSearch2; 3) Functional annotation in GO (Gene Ontology) and EC (Enzyme Commission) based on similarity search results; 4) From EC to metabolic pathway reconstruction by MinPath. Inputs: Just sequencing reads (or assemblies) Outputs: Protein-coding genes (or gene fragments); similarity search; functional annotations (in GO and EC); metabolic pathways.
    Downloads: 1 This Week
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  • 5
    gsasnp2

    gsasnp2

    PubMed ID: 29562348 / DOI: 10.1093/nar/gky175

    * GSA-SNP2 is a successor of GSA-SNP (Nam et al. 2010, NAR web server issue). GSA-SNP2 accepts human GWAS summary data (rs numbers, p-values) or gene-wise p-values and outputs pathway genesets ‘enriched’ with genes associated with the given phenotype. It also provides both local and global protein interaction networks in the associated pathways. * Article: SYoon, HCTNguyen, YJYoo, JKim, BBaik, SKim, JKim, SKim, DNam, "Efficient pathway enrichment and network analysis of GWAS summary data using GSA-SNP2", Nucleic Acids Research, Vol. 46(10), e60(2018)...
    Downloads: 0 This Week
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  • 6

    MoPAC

    The Modular Pipeline for the Analysis of CRISPR screens

    To facilitate the comparison of gene essentialities in two or more cell samples, we propose MoPAC (Modular Pipeline for Analysis of CRISPR screens), a Shiny-driven interactive tool for differential essentiality analysis in CRISPR/Cas9 screens. For installation and usage instructions please refer to the wiki page.
    Downloads: 1 This Week
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  • 7
    The OpenGEREA is a open enrichment analysis framework for gene expression regulation data analysis.
    Downloads: 0 This Week
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  • 8

    Open|SpeedShop

    Open|SpeedShop is an open source multi platform Linux performance tool

    Open|SpeedShop is an open source multi platform Linux performance tool which is targeted to support performance analysis of applications running on both single node and large scale IA64, IA32, EM64T, AMD64, PPC, Blue Gene, ARM and Cray platforms.
    Downloads: 5 This Week
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  • 9

    ParBiBit

    Parallel tool to search biclusters on binary datasets

    ParBiBit is a parallel tool to accelerate the search of biclusters on binary datasets, especially useful for gene expression data. This tool receives as input the expression values of n genes and m samples in a file with ARFF extension and returns a file with the biclustering information.
    Downloads: 0 This Week
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  • 10

    MPICorMat

    Parallel tool to construct correlation similarity matrices

    MPICorMat is a parallel tool to construct correlation similarity matrices as part of the procedure to generate gene co-expression networks. This tool takes as input a matrix with the expression values (a float value) for different genes observed from several samples. It is a parallelization of the first module of the RMTGenNet tool (https://github.com/spficklin/RMTGeneNet). RMTGeneNet users can exchange this CCM module by MPICorMat, benefit from its fast computation to generate the similarity matrix, and then use the similarity matrix as input for the second module (RMM) to construct the final gene co-expression network.
    Downloads: 0 This Week
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  • 11

    CUBiBit

    Tool to search binary biclusters on CUDA-enabled GPUs

    CUBiBit is a parallel tool to accelerate the search of biclusters on binary datasets using CUDA-enabled GPUs. This data mining procedure is especially useful for gene expression data. This tool receives as input a file with ARFF extension that contais the binary values of m attributes and n samples and returns a file with the biclustering information. It is able to exploit the parallel capabilities of manycore NVIDIA GPUS. It also makes use of C++11 multithreading support to accelerate one phase of the algorithm on several CPU cores.
    Downloads: 0 This Week
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  • 12
    Mauve computes and interactively visualizes genome sequence comparisons. Using FastA or GenBank sequence data, Mauve constructs multiple genome alignments that identify large-scale rearrangement, gene gain, gene loss, indels, and nucleotide substutit
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  • 13

    fast_count_multi

    Extremely fast NGS read counter

    ...Benchmark: 8 core 1M annotations for 2Gb sorted reads ~30 seconds compared to ~28 minutes for bedtools multicov. Files include: fast_count_multi - reports all counts and RPKM, multithreading support fast_count_deseq - reports gene counts in deseq compatible format, multithreading support fast_count - reports all counts with no multithreading support. usage ./fast_count_multi num_threads gtf_file bam_file(s) > output Requires bamtools API library at run time, and c++0x for compile. git clone https://github.com/pezmaster31/bamtools cd bamtools mkdir build cd build cmake .. ...
    Downloads: 0 This Week
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  • 14
    HeatmapGenerator
    HeatmapGenerator is a graphical user interface software program written in C++, R, and OpenGL to create customized gene expression heatmaps from RNA-seq and microarray data in medical research. HeatmapGenerator can also be used to make heatmaps in a variety of other non-medical fields. HeatmapGenerator is peer-reviewed published software (http://www.scfbm.org/content/9/1/30). Please cite: [Khomtchouk et al.: "HeatmapGenerator: High performance RNAseq and microarray visualization software suite to examine differential gene expression levels using an R and C++ hybrid computational pipeline." ...
    Downloads: 0 This Week
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  • 15
    The Program to Assemble Spliced Alignments (PASA) is used to automatically incorporate ESTs and full-length cDNAs into gene structure annotations, in the process annotating UTRs, alternative splicing variations, and polyadenylation sites.
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  • 16

    Genetic Algorithms Engine - Blackjack

    A genetic algortihm engine that evolves blackjack basic strategy.

    ...The genetic algorithm engine supports various mutation rates, ranked parental selection, stochastic sampling parental selection, cyclic crossover, crossover at each gene, cloning the best individual each generation, and creating random individuals each generation. To use the genetic algorithm engine to search for a different problem's solution, one needs to program a fitness function, the project settings, and a few virtual functions.
    Downloads: 0 This Week
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  • 17

    PANDA

    Passing Attributes between Networks for Data Assimilation

    PANDA (Passing Attributes between Networks for Data Assimilation), is a message-passing model to gene regulatory network reconstruction. PANDA integrates multiple sources of biological data, including protein-protein interaction, gene expression, and sequence motif information, in order to reconstruct genome-wide, condition-specific regulatory networks. PANDA is also available in other programming languages, including: MATLAB/Octave: (1) https://drive.google.com/a/channing.harvard.edu/file/d/0BwVdzX3nIj6RamtmNVdKYVk1N2c/view?...
    Downloads: 1 This Week
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  • 18
    deFuse is a software package for gene fusion discovery using RNA-Seq data. deFuse .tar.gz bundles will be released periodically on the sourceforge site, see Files. Questions can be posted to the sourceforge discussion forum. The sourceforge wiki is depracated in favour of documentation included with the package. Development of deFuse is on the bitbucket site, linked below.
    Downloads: 1 This Week
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  • 19

    CDPOPgui

    GUI Frontend for CDPOP

    CDPOPgui is a GUI Frontend for CDPOP What is CDPOP? CDPOP (Cost Distance POPulations) is a spatially-explicit simulator of gene-flow in complex landscapes to explain observed population responses and provide a foundation for landscape genetics. The program implements individual-based population modeling with Mendelian inheritance on a resistant landscape. Simulation begins with an initial homogeneous population and followed by divergence through time as functions of individual based movement, breeding and dispersal on a continuous cost surface. ...
    Downloads: 0 This Week
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  • 20

    Kinsolver

    A simulator for biochemical and gene regulatory networks

    Research Article: http://www.sciencedirect.com/science/article/pii/S0898122108006287
    Downloads: 0 This Week
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  • 21
    PARSEC - PAtteRn SEarch / Context

    PARSEC - PAtteRn SEarch / Context

    PARSEC - PAtteRn SEarch and Contextualization

    The characterization of genomic sites is a major challenge in the understanding and exploitation of next generation sequencing data. Most genomic sites are represented by short, degenerated motifs with a scattered distribution and sometimes with biological function (ex: regulation of gene expression, splicing patterns or epigenetics signals). These motifs are associated with a huge amount of noise and thus, the development of a computational platform for accurate detection of genomic sites requires the integration of various large-scale biological data in order to filter out false positives. PARSEC represents an intuitive, modular (easily extensible) and all-in-one solution for the efficient integration of lots of diverse genomic information in order to perform nonlinear localization and characterization of biological sites in a user-friendly environment. ...
    Downloads: 0 This Week
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  • 22
    Software for making Clusters of Orthologous Groups (featuring the new EdgeSearch algorithm). Latest ref: Kristensen DM, Kannan L, Coleman MK, Wolf YI, Sorokin A, Koonin EV, Mushegian A. Bioinformatics 2010.
    Downloads: 0 This Week
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  • 23
    Ab initio gene finder. Formerly known as TIGRscan.
    Downloads: 0 This Week
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  • 24
    The SPELL gene expression explorer searches multiple datasets for related gene expression patterns. Hibbs MA, et al. Exploring the functional landscape of gene expression: Directed search of large microarray compendia. Bioinformatics, 2007.
    Downloads: 0 This Week
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  • 25
    BIL++
    BIL++ is a set of standalone C++ packages for data processing in Bioinformatics (Graph mining, Bayesian networks, Genetic algorithm, Discretization, Gene expression data analysis, Hypothesis testing).
    Downloads: 0 This Week
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