Showing 13 open source projects for "strategy"

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  • 1
    MANTI

    MANTI

    MANTI - Mastering Advanced N-Termini Interpretation

    ...A graphical interface is available as Yoğurtlu_MANTI (a Perl/Tk script) + execut. application versions for Win1x without the need to have Perl installed locally. For a very detailed explanation of script parameters and the evaluation strategy, please consult the extensive manual PDF
    Downloads: 3 This Week
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  • 2

    MToolBox

    A bioinformatics pipeline to analyze mtDNA from NGS data

    MToolBox is a highly automated bioinformatics pipeline to reconstruct and analyze human mitochondrial DNA from high throughput sequencing data. MToolBox includes an updated computational strategy to assemble mitochondrial genomes from Whole Exome and/or Genome Sequencing (PMID: 22669646) and an improved fragment-classify tool (PMID:22139932) for haplogroup assignment, functional and prioritization analysis of mitochondrial variants. MToolBox provides pathogenicity scores, profiles of genome variability and disease-associations for mitochondrial variants. ...
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    Downloads: 10 This Week
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  • 3
    MANTI.pl / muda.pl

    MANTI.pl / muda.pl

    muda.pl - MQ unified data assembler

    ...Maybe also useful for normal proteomics purposes but this script is heavily optimized for protein neo-termini identification and validation. For a more thorough explanation of script parameters and evaluation strategy, please consult the extensive manual PDF.
    Downloads: 1 This Week
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  • 4

    Hamstr

    A tool for directed ortholog search in ESTs and proteins

    ...The program takes a pre-defined core group of orthologous sequences (core orthologs) and a set of sequences from a search taxon as input. HaMStR then combines in a two-step strategy a pHMM based search and a reverse search via BLAST to extend the core ortholog group with novel sequences from the search taxon.
    Downloads: 0 This Week
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  • 5
    ChIP-RNA-seqPRO

    ChIP-RNA-seqPRO

    ChIP-RNA-sequencing-processing (ChIP-RNA-seqPRO)

    ChIP-RNA-seqPRO: A strategy for identifying regions of epigenetic deregulation associated with aberrant transcript splicing and RNA-editing sites. Runnable python scripts packaged together with customized annotation libraries, demo data input and README guide. 9/26 : v1.1 Updated MAIN_IV to debug error thrown by python pandas no longer supporting 'subset'.
    Downloads: 0 This Week
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  • 6
    GenoSuite is a framework developed for proteogenomic analysis. An updated GenoSuite2 is just released where FDRScore (Jones et al. Proteomics 2009) based strategy is used to integrate results from multiple search algorithms. Prokaryotic Proteogenomic Tool(PPT) is developed as a part of GenoSuite framework. PPT is for finding novel translations in prokaryotic genomes and is dependent on Mass Spectrometry based proteomics data and related genome sequence. Some Key features of the tool are...
    Downloads: 0 This Week
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  • 7

    SPA

    SPA: a short peptide assembler for metagenomic data

    The metagenomic paradigm offers the opportunity to study protein families, and therefore the metabolic and functional potential, of the constituent microbes in a community. A nucleotide assembly-based strategy does not fare much better since metagenomic assemblies are typically very fragmented and also leave a large fraction of reads unassembled. We present a method for reconstructing complete protein sequences directly from NGS metagenomic data. Our framework is based on a novel Short Peptide Assembler (SPA) that assembles protein sequences from their constituent peptide fragments identified on short reads. ...
    Downloads: 1 This Week
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  • 8
    FineSplice

    FineSplice

    Enhanced splice junction detection and estimation from RNA-Seq data

    ...Following alignment with TopHat2 using known transcript annotations, FineSplice takes as input the resulting BAM file and outputs a confident set of expressed splice junctions with the corresponding read counts. Potential false positives arising from spurious alignments are filtered out via a semi-supervised anomaly detection strategy based on logistic regression. Multiple mapping reads with a unique location after filtering are rescued and reallocated to the most reliable candidate location. FineSplice requires Python 2.x (>= 2.6) with the following modules installed: pysam (http://code.google.com/p/pysam/) and scikit-learn (http://scikit-learn.org/). ...
    Downloads: 2 This Week
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  • 9

    DyMMM

    Dynamic Multispecies Metabolic Modeling framework

    ...Genome-scale dynamic modeling of the competition between Rhodoferax and Geobacter in anoxic subsurface environments. The ISME journal. Zhuang, K., Ma, E., Lovley, D. R., & Mahadevan, R. (2012). The design of long-term effective uranium bioremediation strategy using a community metabolic model. Biotechnology and Bioengineering.
    Downloads: 0 This Week
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  • 10
    3D Realtime Simulation der Evolution des Lebens. Frei erweiterbares Gen/Mutations-System mit Direct3D-Engine. <b>Wichtig ".NET 2.0 beta"-basierent !</b> Also wird zumindest ein Visual Basic 2005 Express Beta benötigt.
    Downloads: 0 This Week
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  • 11

    clinicalStudyTracker

    Clinical study tracker tracks case study members through activities.

    Developed at Medical Research Council UK to meet a common clinical trial need to track various types of clinical data. Users log dates of completed tasks against participant ID. Simple, useable, reduces lost data! Makes graphical progress reports.
    Downloads: 0 This Week
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  • 12
    Program described in the paper: MUDE: A new approach for optimizing sensitivity in the target-decoy search strategy for large-scale peptide/protein identification, 2010. By Cerqueira, Fabio; Graber, Armin; Schwikowski, Benno; Baumgartner, Christian.
    Downloads: 0 This Week
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  • 13
    SISSIz is a program for randomizing multiple sequence alignments preserving dinucleotide content. It can be used as a control strategy for comparative noncoding RNA gene prediction programs and as a standalone RNA gene finder.
    Downloads: 0 This Week
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