Search Results for "far"

Most current approaches analyze metagenomic data with the participation of reference genomes. However, novel microbial communities extend far beyond the coverage of reference databases and de novo metagenome assembly from complex microbial communities still remains a great challenge. Here we present a novel experimental and bioinformatic framework, metaSort, for effective construction of bacterial genomes from metagenomic samples. MetaSort provides a sorted mini-metagenome approach based on flow cytometry and single-cell sequencing methodologies, and employs new computational algorithms to efficiently recover high-quality genomes from the sorted mini-metagenome by the complementary of the original metagenome. ...

...Using a provided adapter sequence, it generates variations of this sequence and stores them in a hash table. The reads can then be directly matched against the hash. It is far more time efficient than doing alignment.

High-throughput next generation sequencing (NGS) technology has quickly emerged as a powerful tool in many aspects of biomedical research. However, along with its rapid development, the data magnitude and analysis complexity for NGS far exceed the capacity and capability of traditional small-scale computing facilities, such as multithreading algorithms on standalone workstations. To address this issue, here we present a solution using the ever-increasing supply of processing power by massive parallel processing (MPP) systems.

A set of very optimized tools for indexing/querying huge genomes/files. Provided so far: a very fast exact mapper, and an unconstrained split-mapper

...The accumulation of mutations may instead be responsible for a "maturation" which may have real physical meaning rather than being an amorphous concept. Scientists such as Donald Williamson and Lynn Margulis have suggested similar ideas but perhaps not going as far as this project assumes. This software converted the Catalogue of Life, catalogueoflife.org, into a gedcom format. It no longer works due to the Catalogue's database format change. This present project extends the gedcom format for use in systematics or species categorization. All named taxonomic levels are assumed to have originally been individual species and the software/database outputs all species as female until hybridization events can be added manually. ...

Bioinformatics is commonly understood as work with the DNA and protein sequences. However databases and computational analysis were tried on other objects far before these sequences became widely available. This work is about analysis of spatial movement

...Terms for these subdomains have partially been implemented in the main file, **genepio.owl**, which imports terms from over 25 OboFoundry.org ontologies. Also we have added a number of terms that so far haven't been covered via OboFoundry. Recognizing that GenEpiO encompasses many domains, we are advocating a consortium approach for enhancing its content via interested parties that need particular domain terminology.