Open Source Python Artificial Intelligence Software - Page 14

Python Artificial Intelligence Software

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  • 1
    OpenSquilla

    OpenSquilla

    Token-Efficient AI Agent with same budget, higher intelligence density

    OpenSquilla is a token-efficient microkernel AI agent runtime designed for CLI, web UI, and chat-based workflows. It routes each turn through a shared loop that can select lower-cost models when appropriate while preserving tool dispatch, retries, memory, and decision logging. The project supports multiple LLM providers through a pluggable provider layer, making it adaptable to different model ecosystems. It includes persistent memory, built-in web search, on-device embeddings, and sandboxing for safer execution. OpenSquilla is designed for users who want stronger agent capabilities without wasting tokens on every interaction. Its main value is combining cost-aware routing, durable context, and multi-channel agent execution in one local runtime.
    Downloads: 9 This Week
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  • 2
    Protenix

    Protenix

    A trainable PyTorch reproduction of AlphaFold 3

    Protenix is an open-source, trainable PyTorch reimplementation of AlphaFold 3, developed by ByteDance with the goal of democratizing high-accuracy protein structure prediction for computational biology and drug-discovery research. Protenix provides a complete pipeline for turning protein sequences (with optional MSA / sequence alignment) or structural inputs (e.g. PDB/CIF) into full 3D atomic-level structure predictions. It supports both “full” models and lightweight variants such as “Protenix-Mini,” offering a trade-off between speed/compute cost and predictive accuracy — making structure prediction accessible even in resource-constrained environments. The project also includes support for constraints (e.g., specifying residue- or atom-level contact constraints, or pocket constraints) to guide predictions toward biologically or experimentally relevant conformations, which enhances its utility for tasks like modeling complexes, ligands, or antibody–antigen interactions.
    Downloads: 9 This Week
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  • 3
    Punica

    Punica

    Serving multiple LoRA finetuned LLM as one

    Punica is a system designed to efficiently serve multiple LoRA-fine-tuned large language models within a shared GPU environment. LoRA is a parameter-efficient fine-tuning method that allows developers to adapt large pretrained models to specific tasks by adding lightweight adapter layers rather than retraining the entire model. Punica introduces a serving architecture that allows multiple LoRA adapters to share the same base model during inference, significantly reducing memory consumption and computational overhead. The system includes specialized CUDA kernels that enable batched GPU operations across different LoRA models simultaneously. This design allows a single GPU cluster to host many task-specific models while maintaining high throughput and minimal latency. The architecture also includes scheduling mechanisms that coordinate requests from multiple tenants and distribute workloads efficiently across available resources.
    Downloads: 9 This Week
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  • 4
    RAG API

    RAG API

    ID-based RAG FastAPI: Integration with Langchain and PostgreSQL

    rag_api is an open-source REST API for building Retrieval-Augmented Generation (RAG) systems using LLMs like GPT. It lets users index documents, search semantically, and retrieve relevant content for use in generative AI workflows. Designed for rapid prototyping, it is ideal for chatbot development, document assistants, and knowledge-based LLM apps.
    Downloads: 9 This Week
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  • 5
    SHAP

    SHAP

    A game theoretic approach to explain the output of ml models

    SHAP (SHapley Additive exPlanations) is a game theoretic approach to explain the output of any machine learning model. It connects optimal credit allocation with local explanations using the classic Shapley values from game theory and their related extensions. While SHAP can explain the output of any machine learning model, we have developed a high-speed exact algorithm for tree ensemble methods. Fast C++ implementations are supported for XGBoost, LightGBM, CatBoost, scikit-learn and pyspark tree models. To understand how a single feature effects the output of the model we can plot the SHAP value of that feature vs. the value of the feature for all the examples in a dataset. Since SHAP values represent a feature's responsibility for a change in the model output, the plot below represents the change in predicted house price as RM (the average number of rooms per house in an area) changes.
    Downloads: 9 This Week
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  • 6
    Skill Scanner

    Skill Scanner

    Security Scanner for Agent Skills

    This repository is a public security-focused scanning tool intended to analyze and assess AI agent skills for potential issues, quality concerns, and vulnerabilities. It acts as a scanner that inspects Agent Skills packages to flag structural problems, inconsistencies, or security flaws before they are deployed or integrated into agent workflows. Because agent skills can contain executable instructions and logic, scanning them for risky patterns is essential to prevent inadvertent exploitation when used by intelligent systems. The tool supports maintainers and community contributors in automating quality checks and enforcing conventions across skill sets in a standardized way. While still evolving with contributions and issue discussions, it shows the community’s interest in building safer AI ecosystems around reusable capabilities. The scanner also serves as a foundation for more sophisticated vetting frameworks that might be incorporated into CI/CD pipelines.
    Downloads: 9 This Week
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  • 7
    Style-Bert-VITS2

    Style-Bert-VITS2

    Style-Bert-VITS2: Bert-VITS2 with more controllable voice styles

    Style-Bert-VITS2 is a text-to-speech system based on Bert-VITS2 that focuses on highly controllable voice styles and emotional expression. It takes the original Bert-VITS2 v2.1 and its Japanese-Extra variant and extends them so you can control emotion and speaking style with fine-grained intensity, not just choose a generic tone. The project targets both power users and beginners: Windows users without Git or Python can install and run it using bundled .bat scripts, while advanced users can work with virtual environments, uv, and Python tooling. It includes a full GUI editor to script dialogue, set different styles per line, edit dictionaries, and save/load projects, plus a separate web UI and Colab notebooks for training and experimentation. For those who only need synthesis, the project is published as a Python library (pip install style-bert-vits2) and can run on CPU without an NVIDIA GPU, though training still requires GPU hardware.
    Downloads: 9 This Week
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  • 8
    Thinc

    Thinc

    A refreshing functional take on deep learning

    Thinc is a lightweight deep learning library that offers an elegant, type-checked, functional-programming API for composing models, with support for layers defined in other frameworks such as PyTorch, TensorFlow and MXNet. You can use Thinc as an interface layer, a standalone toolkit or a flexible way to develop new models. Previous versions of Thinc have been running quietly in production in thousands of companies, via both spaCy and Prodigy. We wrote the new version to let users compose, configure and deploy custom models built with their favorite framework. Switch between PyTorch, TensorFlow and MXNet models without changing your application, or even create mutant hybrids using zero-copy array interchange. Develop faster and catch bugs sooner with sophisticated type checking. Trying to pass a 1-dimensional array into a model that expects two dimensions? That’s a type error. Your editor can pick it up as the code leaves your fingers.
    Downloads: 9 This Week
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  • 9
    XHS-Downloader

    XHS-Downloader

    GUI/CLI tool for downloading Xiaohongshu

    XHS-Downloader is a GUI/CLI tool for downloading Xiaohongshu (Little Red Book) content without watermarks, supporting both graphics and video posts. Prebuilt packages for Windows and macOS are available from Releases and GitHub Actions artifacts, so most users can run it by unzipping and launching the included executable. The project offers two execution paths—run the compiled app or run from source—and documents default download and configuration paths to simplify first use. Recent releases add format support like JPEG and HEIC, clipboard-listening mode improvements, author-based archiving, SOCKS/HTTP proxy options, and the ability to set the file’s modification time to the post’s publish time for cleaner library organization. There is an active issues/discussions area with community tips, including approaches that use Selenium to acquire cookies and user agents for more reliable downloads.
    Downloads: 9 This Week
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  • 10
    YandexStation

    YandexStation

    Management of Yandex Station and other smart home devices

    YandexStation is a Home Assistant custom component that integrates Yandex-branded smart speakers and other devices with Alice into a unified smart home automation environment. It supports both local and cloud control, depending on the device type, with Yandex speakers often supporting both modes and third-party speakers typically limited to cloud control. The integration exposes playback and volume controls, as well as text-to-speech capabilities that send spoken messages in Alice’s voice directly to the speakers. It also lets you send arbitrary text commands as if you were talking to Alice, enabling scenarios such as “play my music,” launching routines, or querying information via Home Assistant automations. In local control mode, the component can read back what is currently playing, including album art, and supports seeking and track skipping, which is more limited in cloud-only mode.
    Downloads: 9 This Week
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  • 11
    gpt-oss

    gpt-oss

    gpt-oss-120b and gpt-oss-20b are two open-weight language models

    gpt-oss is OpenAI’s open-weight family of large language models designed for powerful reasoning, agentic workflows, and versatile developer use cases. The series includes two main models: gpt-oss-120b, a 117-billion parameter model optimized for general-purpose, high-reasoning tasks that can run on a single H100 GPU, and gpt-oss-20b, a lighter 21-billion parameter model ideal for low-latency or specialized applications on smaller hardware. Both models use a native MXFP4 quantization for efficient memory use and support OpenAI’s Harmony response format, enabling transparent full chain-of-thought reasoning and advanced tool integrations such as function calling, browsing, and Python code execution. The repository provides multiple reference implementations—including PyTorch, Triton, and Metal—for educational and experimental use, as well as example clients and tools like a terminal chat app and a Responses API server.
    Downloads: 9 This Week
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  • 12
    labelme Image Polygonal Annotation

    labelme Image Polygonal Annotation

    Image polygonal annotation with Python

    Labelme is a graphical image annotation tool. It is written in Python and uses Qt for its graphical interface. Image annotation for polygon, rectangle, circle, line and point. Image flag annotation for classification and cleaning. Video annotation. (video annotation). GUI customization (predefined labels / flags, auto-saving, label validation, etc). Exporting VOC-format dataset for semantic/instance segmentation. (semantic segmentation, instance segmentation). Exporting COCO-format dataset for instance segmentation. (instance segmentation). The first time you run labelme, it will create a config file in ~/.labelmerc. You can edit this file and the changes will be applied the next time that you launch labelme. If you would prefer to use a config file from another location, you can specify this file with the --config flag.
    Downloads: 9 This Week
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  • 13
    nanoGPT

    nanoGPT

    The simplest, fastest repository for training/finetuning models

    NanoGPT is a minimalistic yet powerful reimplementation of GPT-style transformers created by Andrej Karpathy for educational and research use. It distills the GPT architecture into a few hundred lines of Python code, making it far easier to understand than large, production-scale implementations. The repo is organized with a training pipeline (dataset preprocessing, model definition, optimizer, training loop) and inference script so you can train a small GPT on text datasets like Shakespeare or custom corpora. It emphasizes readability and clarity: the training loop is cleanly written, and the code avoids heavy abstractions, letting students follow the architecture step by step. While simple, it can still train non-trivial models on modern GPUs and generate coherent text. The project has become widely used in tutorials, courses, and experiments for people learning how transformers work under the hood.
    Downloads: 9 This Week
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  • 14
    openTSNE

    openTSNE

    Extensible, parallel implementations of t-SNE

    openTSNE is a modular Python implementation of t-Distributed Stochasitc Neighbor Embedding (t-SNE) [1], a popular dimensionality-reduction algorithm for visualizing high-dimensional data sets. openTSNE incorporates the latest improvements to the t-SNE algorithm, including the ability to add new data points to existing embeddings [2], massive speed improvements [3] [4] [5], enabling t-SNE to scale to millions of data points, and various tricks to improve the global alignment of the resulting visualizations.
    Downloads: 9 This Week
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  • 15
    reverse-SynthID

    reverse-SynthID

    Reverse engineering Gemini's SynthID detection

    Reverse-SynthID is a research-focused project that analyzes and reverse-engineers Google’s SynthID watermarking system used in AI-generated images. It leverages signal processing and spectral analysis techniques to identify hidden watermark patterns without access to proprietary encoding methods. The project introduces a multi-resolution “SpectralCodebook” that maps watermark characteristics across different image sizes. Using this approach, it can detect SynthID watermarks with high accuracy and selectively reduce or remove them through frequency-domain manipulation. Unlike traditional image degradation methods, it performs targeted, minimally invasive adjustments that preserve image quality. Overall, Reverse-SynthID serves as a technical exploration of AI watermark robustness, detection, and removal strategies.
    Downloads: 9 This Week
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  • 16
    skfolio

    skfolio

    Python library for portfolio optimization built on top of scikit-learn

    skfolio is a Python library designed for portfolio optimization and financial risk management that integrates closely with the scikit-learn ecosystem. The project provides a unified machine learning-style framework for building, validating, and comparing portfolio allocation strategies using financial data. By following the familiar scikit-learn API design, the library allows quantitative researchers and developers to apply techniques such as model selection, cross-validation, and hyperparameter tuning to portfolio construction workflows. It supports a wide range of allocation methods, from classical mean-variance optimization to modern techniques that rely on clustering, factor models, and risk-based allocations. The framework also includes tools for evaluating portfolio performance under different market conditions, enabling users to test robustness and reduce the risk of overfitting.
    Downloads: 9 This Week
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  • 17
    spaCy

    spaCy

    Industrial-strength Natural Language Processing (NLP)

    spaCy is a library built on the very latest research for advanced Natural Language Processing (NLP) in Python and Cython. Since its inception it was designed to be used for real world applications-- for building real products and gathering real insights. It comes with pretrained statistical models and word vectors, convolutional neural network models, easy deep learning integration and so much more. spaCy is the fastest syntactic parser in the world according to independent benchmarks, with an accuracy within 1% of the best available. It's blazing fast, easy to install and comes with a simple and productive API.
    Downloads: 9 This Week
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  • 18
    AI Runner

    AI Runner

    Offline inference engine for art, real-time voice conversations

    AI Runner is an offline inference engine designed to run a collection of AI workloads on your own machine, including image generation for art, real-time voice conversations, LLM-powered chatbots and automated workflows. It is implemented as a desktop-oriented Python application and emphasizes privacy and self-hosting, allowing users to work with text-to-speech, speech-to-text, text-to-image and multimodal models without sending data to external services. At the core of its LLM stack is a mode-based architecture with specialized “modes” such as Author, Code, Research, QA and General, and a workflow manager that automatically routes user requests to the right agent based on the task. The project has a strong focus on developer ergonomics, with thorough development guidelines, environment configuration using .env variables, and a clear structure for tests, tools and agents.
    Downloads: 8 This Week
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  • 19
    Aden Hive

    Aden Hive

    Outcome driven agent development framework that evolves

    Hive is an open-source agent development framework that helps developers build autonomous, reliable, self-improving AI agents by letting them describe goals in ordinary natural language instead of hand-coding detailed workflows. Rather than manually defining execution graphs, Hive’s coding agent generates the agent graph, connection code, and test cases based on your high-level objectives, enabling outcome-driven agent creation that fits real business processes. Once deployed, agents can capture failure data, evolve automatically to meet their success criteria, and redeploy without constant manual intervention, delivering continual improvement over time. The framework also includes human-in-the-loop nodes, credential management, cost and budget controls, and real-time observability so teams can monitor execution and intervene as needed. Hive is designed for production environments and supports a wide range of large language models, local models, and business system connectivity.
    Downloads: 8 This Week
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  • 20
    AlphaGenome

    AlphaGenome

    Programmatic access to the AlphaGenome model

    The AlphaGenome API provides access to AlphaGenome, Google DeepMind’s unifying model for deciphering the regulatory code within DNA sequences. This repository contains client-side code, examples, and documentation to help you use the AlphaGenome API. AlphaGenome offers multimodal predictions, encompassing diverse functional outputs such as gene expression, splicing patterns, chromatin features, and contact maps. The model analyzes DNA sequences of up to 1 million base pairs in length and can deliver predictions at single-base-pair resolution for most outputs. AlphaGenome achieves state-of-the-art performance across a range of genomic prediction benchmarks, including numerous diverse variant effect prediction tasks.
    Downloads: 8 This Week
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  • 21
    Anthropic SDK Python

    Anthropic SDK Python

    Provides convenient access to the Anthropic REST API from any Python 3

    The anthropic-sdk-python repository is the official Python client library for interacting with the Anthropic (Claude) REST API. It is designed to provide a user-friendly, type-safe, and asynchronous/synchronous capable interface for making chat/completion requests to models like Claude. The library includes definitions for all request and response parameters using Python typed objects, automatically handles serialization and deserialization, and wraps HTTP logic (timeouts, retries, error mapping) so that developers can call the API in a clean, high-level way. The SDK supports both synchronous and asynchronous usage (via async/await) depending on context. Importantly, it also supports streaming responses via Server-Sent Events (SSE) so that large outputs can be consumed incrementally rather than waiting for the full response. The client offers helper abstractions for tools (function-style “tools”) and streaming utilities for building interactive agents.
    Downloads: 8 This Week
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  • 22
    Axolotl

    Axolotl

    Go ahead and axolotl questions

    Axolotl is a powerful and flexible framework for fine-tuning large language models on custom datasets. Built for researchers and developers, Axolotl simplifies the process of adapting LLMs for specific tasks, including chat, code generation, and instruction following. It supports a wide variety of model architectures and offers out-of-the-box optimization strategies for efficient training.
    Downloads: 8 This Week
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  • 23
    BudouX

    BudouX

    Standalone, small, language-neutral

    Standalone. Small. Language-neutral. BudouX is the successor to Budou, the machine learning-powered line break organizer tool. It is standalone. It works with no dependency on third-party word segmenters such as Google cloud natural language API. It is small. It takes only around 15 KB including its machine learning model. It's reasonable to use it even on the client-side. It is language-neutral. You can train a model for any language by feeding a dataset to BudouX’s training script.
    Downloads: 8 This Week
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  • 24
    CAMEL AI

    CAMEL AI

    Finding the Scaling Law of Agents. A multi-agent framework

    The rapid advancement of conversational and chat-based language models has led to remarkable progress in complex task-solving. However, their success heavily relies on human input to guide the conversation, which can be challenging and time-consuming. This paper explores the potential of building scalable techniques to facilitate autonomous cooperation among communicative agents and provide insight into their "cognitive" processes. To address the challenges of achieving autonomous cooperation, we propose a novel communicative agent framework named role-playing. Our approach involves using inception prompting to guide chat agents toward task completion while maintaining consistency with human intentions. We showcase how role-playing can be used to generate conversational data for studying the behaviors and capabilities of chat agents, providing a valuable resource for investigating conversational language models.
    Downloads: 8 This Week
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  • 25
    Cheshire Cat AI

    Cheshire Cat AI

    AI agent microservice

    Cheshire Cat AI Core is an open-source framework for building customizable AI agents as scalable microservices, designed to integrate conversational intelligence into applications through an API-first architecture. It allows developers to create advanced AI assistants that can interact through WebSockets, REST APIs, and embedded chat interfaces, making it suitable for both backend services and user-facing applications. The framework includes built-in support for retrieval-augmented generation using vector databases such as Qdrant, enabling agents to incorporate external knowledge and documents into their responses. It is highly extensible through a plugin system that supports custom tools, event hooks, and workflows, giving developers fine-grained control over agent behavior and interactions. Cheshire Cat also supports multi-user environments with granular permissions and identity provider integration, making it suitable for enterprise use cases.
    Downloads: 8 This Week
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