Python Agentic AI Tools

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Browse free open source Python Agentic AI Tools and projects below. Use the toggles on the left to filter open source Python Agentic AI Tools by OS, license, language, programming language, and project status.

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  • 1
    GELab-Zero

    GELab-Zero

    GUI Exploration Lab. One of the best GUI agent solutions

    GELab-Zero is an open-source “GUI Agent” framework aiming to automate interactions with graphical user interfaces (GUIs), combining both the agent model and all supporting infrastructure — including inference, input orchestration, and GUI automation logic — in a plug-and-play package that runs locally, without cloud dependencies. The idea is to let developers or users harness an AI agent that can simulate clicking, typing, reading UI elements, and interacting with apps in a human-like way via the GUI, which can enable tasks like automated testing, scriptable workflows, or even autonomous usage of GUI-based applications. Because GELab-Zero is fully open-source and doesn’t require external services, it offers privacy and control: everything runs locally under your control. The project provides a lightweight base model (4B parameters in its public release) that can run on modest hardware (depending on quantization), making it more accessible than many large-scale AI solutions.
    Downloads: 2 This Week
    Last Update:
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  • 2
    Habitat-Lab

    Habitat-Lab

    A modular high-level library to train embodied AI agents

    Habitat-Lab is a modular high-level library for end-to-end development in embodied AI. It is designed to train agents to perform a wide variety of embodied AI tasks in indoor environments, as well as develop agents that can interact with humans in performing these tasks. Allowing users to train agents in a wide variety of single and multi-agent tasks (e.g. navigation, rearrangement, instruction following, question answering, human following), as well as define novel tasks. Configuring and instantiating a diverse set of embodied agents, including commercial robots and humanoids, specifying their sensors and capabilities. Providing algorithms for single and multi-agent training (via imitation or reinforcement learning, or no learning at all as in SensePlanAct pipelines), as well as tools to benchmark their performance on the defined tasks using standard metrics.
    Downloads: 2 This Week
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  • 3
    Hello-Agents

    Hello-Agents

    Building an Intelligent Agent from Scratch

    Hello Agents is an open educational project designed to teach developers how to understand, design, and build AI-native agents from the ground up through structured tutorials and practical examples. The project focuses on guiding learners beyond superficial framework usage toward deeper comprehension of agent architecture, reasoning loops, and real-world implementation patterns. It walks users through core concepts such as ReAct-style reasoning, tool usage, memory handling, and multi-step task execution, enabling hands-on experimentation with modern LLM-powered agent systems. The repository is structured as a progressive learning path, combining theory, exercises, and runnable code so users can incrementally build more capable agents. Its goal is to demystify agent engineering and help developers move from simple prompt scripts to robust autonomous systems.
    Downloads: 2 This Week
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  • 4
    IntentKit

    IntentKit

    An open and fair framework for everyone to build AI agents

    IntentKit is a natural language understanding (NLU) library focused on intent recognition and entity extraction, enabling developers to build conversational AI applications.
    Downloads: 2 This Week
    Last Update:
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  • 5
    LLMStack

    LLMStack

    No-code multi-agent framework to build LLM Agents, workflows

    LLMStack is a no-code platform for building generative AI agents, workflows and chatbots, connecting them to your data and business processes. Build tailor-made generative AI agents, applications and chatbots that cater to your unique needs by chaining multiple LLMs. Seamlessly integrate your own data, internal tools and GPT-powered models without any coding experience using LLMStack's no-code builder. Trigger your AI chains from Slack or Discord. Deploy to the cloud or on-premise.
    Downloads: 2 This Week
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  • 6
    Langroid

    Langroid

    Harness LLMs with Multi-Agent Programming

    Given the remarkable abilities of recent Large Language Models (LLMs), there is an unprecedented opportunity to build intelligent applications powered by this transformative technology. The top question for any enterprise is: how best to harness the power of LLMs for complex applications? For technical and practical reasons, building LLM-powered applications is not as simple as throwing a task at an LLM system and expecting it to do it. Effectively leveraging LLMs at scale requires a principled programming framework. In particular, there is often a need to maintain multiple LLM conversations, each instructed in different ways, and "responsible" for different aspects of a task.
    Downloads: 2 This Week
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  • 7
    Letta

    Letta

    Letta (formerly MemGPT) is a framework for creating LLM services

    Letta is an AI-powered task automation framework designed to handle workflow automation, natural language commands, and AI-driven decision-making.
    Downloads: 2 This Week
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  • 8
    MedgeClaw

    MedgeClaw

    Open-source AI research assistant for biomedicine

    MedgeClaw is a specialized AI-powered research assistant tailored for biomedical and scientific workflows, built on top of OpenClaw and Claude Code architectures. It integrates a large library of domain-specific skills, enabling it to perform complex analyses in areas such as genomics, drug discovery, and clinical research. The system connects conversational interfaces with computational environments, allowing users to initiate research tasks through messaging platforms while the backend executes analyses using tools like R and Python. It includes a real-time dashboard that displays progress, generated code, and outputs, providing transparency throughout the research process. MedgeClaw also supports reproducibility by generating structured reports and maintaining consistent environments through containerization. Its architecture combines conversational AI, automated pipelines, and scientific tooling into a unified workflow.
    Downloads: 2 This Week
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  • 9
    MemPalace

    MemPalace

    The highest-scoring AI memory system ever benchmarked

    MemPalace is an open-source AI memory system designed to solve one of the most persistent limitations of large language models: the loss of context between sessions. Instead of relying on summarization or selective extraction like most memory tools, it takes a radically different approach by storing conversations in their entirety and making them retrievable through structured organization and semantic search. The system is inspired by the classical “memory palace” mnemonic technique, organizing information into hierarchical spaces such as wings, rooms, and halls, which allows AI agents to navigate past knowledge in a more contextual and intuitive way. It operates fully locally using tools like ChromaDB, meaning it requires no API keys, cloud services, or external dependencies once installed. MemPalace emphasizes fidelity over compression, preserving full conversational history to maintain reasoning, nuance, and decision-making context that is typically lost in other systems.
    Downloads: 2 This Week
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  • Build Agents and Models on One Platform Icon
    Build Agents and Models on One Platform

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  • 10
    MetaGPT

    MetaGPT

    The Multi-Agent Framework

    The Multi-Agent Framework: Given one line Requirement, return PRD, Design, Tasks, Repo. Assign different roles to GPTs to form a collaborative software entity for complex tasks. MetaGPT takes a one-line requirement as input and outputs user stories / competitive analysis/requirements/data structures / APIs / documents, etc. Internally, MetaGPT includes product managers/architects/project managers/engineers. It provides the entire process of a software company along with carefully orchestrated SOPs.
    Downloads: 2 This Week
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  • 11
    Multi-Agent Particle Envs

    Multi-Agent Particle Envs

    Code for a multi-agent particle environment used in a paper

    Multiagent Particle Environments is a lightweight framework for simulating multi-agent reinforcement learning tasks in a continuous observation space with discrete action settings. It was originally developed by OpenAI and used in the influential paper Multi-Agent Actor-Critic for Mixed Cooperative-Competitive Environments. The environment provides simple particle-based worlds with simulated physics, where agents can move, communicate, and interact with each other. Scenarios are designed to model cooperative, competitive, and mixed interactions among agents, making it useful for testing algorithms in multi-agent settings. The project includes built-in scenarios such as navigation to landmarks, cooperative tasks, and adversarial setups. Although archived, its concepts and code structure remain foundational for more advanced libraries like PettingZoo, which extended and maintained this environment.
    Downloads: 2 This Week
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  • 12
    NagaAgent

    NagaAgent

    A simple yet powerful agent framework for personal assistants

    NagaAgent is an experimental framework for building interactive virtual agents capable of autonomous reasoning, dialog, and task execution using components that mirror human cognitive patterns. It provides abstractions for representing goals, context, and state so that agents can plan sequences of actions, evaluate outcomes, and adjust behavior over time. The project includes mechanisms for semantic memory, reasoning pipelines, and integration points with external data sources and language models so that agents can interpret natural language instructions and produce coherent multi-step outputs. Rather than being a simple chatbot, NagaAgent emphasizes persistent thought cycles, context retention, and the ability to decompose complex tasks into smaller executable units, earning it a place in research explorations of agent design. Its architecture facilitates extensibility, allowing developers to plug in different reasoning modules or knowledge sources depending on the domain of use.
    Downloads: 2 This Week
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  • 13
    Nextpy

    Nextpy

    Self-Modifying Framework from the Future

    NextPy is a Python-based framework for building AI-powered automation agents, allowing developers to create intelligent, rule-based workflows.
    Downloads: 2 This Week
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  • 14
    Notte

    Notte

    Opensource browser using agents

    Notte is an open-source browser framework that enables the development and deployment of web-based AI agents. It introduces a perception layer that transforms web pages into structured, navigable maps described in natural language, allowing agents to interact with the internet more effectively. Notte is designed for building scalable and efficient browser-based AI applications.
    Downloads: 2 This Week
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  • 15
    Parlant

    Parlant

    The behavior guidance framework for customer-facing LLM agents

    Parlant is a lightweight speech-to-text and text-to-speech framework designed for real-time AI-driven voice applications.
    Downloads: 2 This Week
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  • 16
    Phidata

    Phidata

    Build multi-modal Agents with memory, knowledge, tools and reasoning

    Phidata is an open source platform for building, deploying, and monitoring AI agents. It enables users to create domain-specific agents with memory, knowledge, and external tools, enhancing AI capabilities for various tasks. The platform supports a range of large language models and integrates seamlessly with different databases, vector stores, and APIs. Phidata offers pre-configured templates to accelerate development and deployment, allowing users to quickly go from building agents to shipping them into production. It includes features like real-time monitoring, agent evaluations, and performance optimization tools, ensuring the reliability and scalability of AI solutions. Phidata also allows developers to bring their own cloud infrastructure, offering flexibility for custom setups. The platform provides robust support for enterprises, including security features, agent guardrails, and automated DevOps for smoother deployment processes.
    Downloads: 2 This Week
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  • 17
    Portia SDK Python

    Portia SDK Python

    Portia Labs Python SDK for building agentic workflows

    portia‑sdk‑python is an open-source Python SDK by Portia Labs for creating reliable, stateful, authenticated multi-agent AI workflows. It supports tool-backed agents capable of real-world interactions—like web browsing, API access, and human-in-the-loop clarifications—while maintaining transparency and auditability through structured plans and execution hooks. Designed for production environments, the SDK integrates with local or cloud LLMs (e.g. OpenAI, Anthropic, Mistral, Gemini) and supports extensive tool registries, session handling, and memory management.
    Downloads: 2 This Week
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  • 18
    Potpie

    Potpie

    Create custom engineering agents for your codebase

    Potpie is an AI-powered data analysis tool that automates the exploration and visualization of datasets, assisting users in uncovering insights without extensive coding.
    Downloads: 2 This Week
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  • 19
    PraisonAI

    PraisonAI

    PraisonAI application combines AutoGen and CrewAI or similar framework

    PraisonAI application combines AutoGen and CrewAI or similar frameworks into a low-code solution for building and managing multi-agent LLM systems, focusing on simplicity, customization, and efficient human-agent collaboration. Chat with your ENTIRE Codebase. Praison AI, leveraging both AutoGen and CrewAI or any other agent framework, represents a low-code, centralized framework designed to simplify the creation and orchestration of multi-agent systems for various LLM applications, emphasizing ease of use, customization, and human-agent interaction.
    Downloads: 2 This Week
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  • 20
    PromethAI

    PromethAI

    Open-source framework that gives you AI Agents

    PromethAI-Backend is a backend framework for AI-driven automation and knowledge extraction. It is designed to integrate with large language models (LLMs) to provide AI-enhanced workflows, including content generation, summarization, and data analysis.
    Downloads: 2 This Week
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  • 21
    Quark Agent

    Quark Agent

    Quark Agent - Your AI-powered Android APK Analyst

    With Quark Agent, you can perform analyses using only natural language. It creates Quark Script code following your ideas and adjusts the code promptly as you provide feedback.
    Downloads: 2 This Week
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  • 22
    RWARE

    RWARE

    MuA multi-agent reinforcement learning environment

    robotic-warehouse is a simulation environment and framework for robotic warehouse automation, enabling research and development of AI and robotic agents to manage warehouse logistics, such as item picking and transport.
    Downloads: 2 This Week
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  • 23
    RecursiveMAS

    RecursiveMAS

    Offical Implementation for "Recursive Multi-Agent Systems"

    RecursiveMAS is an advanced multi-agent AI framework that introduces a recursive collaboration mechanism to improve reasoning and problem-solving across multiple agents. Instead of treating agents as independent units exchanging text outputs, it connects them through a shared latent computation loop, allowing internal “thought states” to be passed and refined iteratively. This recursive structure enables agents to build on each other’s intermediate reasoning, leading to deeper and more coherent solutions. The system uses a lightweight module called RecursiveLink to transfer and transform latent representations between agents, enabling seamless interaction even across heterogeneous models. It also incorporates an inner–outer loop training approach that optimizes the entire system collectively rather than tuning each agent separately. This design improves efficiency, reduces token usage, and stabilizes learning during iterative reasoning.
    Downloads: 2 This Week
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  • 24
    SWE-agent

    SWE-agent

    SWE-agent takes a GitHub issue and tries to automatically fix it

    SWE-agent turns LMs (e.g. GPT-4) into software engineering agents that can resolve issues in real GitHub repositories. On the SWE-bench, the SWE-agent resolves 12.47% of issues, achieving state-of-the-art performance on the full test set. We accomplish our results by designing simple LM-centric commands and feedback formats to make it easier for the LM to browse the repository, and view, edit, and execute code files. We call this an Agent-Computer Interface (ACI).
    Downloads: 2 This Week
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  • 25
    SafeClaw

    SafeClaw

    Chat with it via text and voice

    SafeClaw is an open-source, entirely local alternative to cloud-based AI assistants like OpenClaw, enabling users to build a personal assistant that runs on their own machine without incurring API usage charges or exposing data to third-party services. It emphasizes privacy and predictability by using traditional programming, rule-based intent parsing, and established machine learning tools rather than large language models, meaning there are no per-token API costs and deterministic behavior. The assistant offers features such as voice control using fully local speech-to-text (Whisper) and text-to-speech (Piper) capabilities, news aggregation with extractive summarization, and smart home or Bluetooth device control. SafeClaw supports multiple channels, including CLI and Telegram, and avoids prompt injection risk because it doesn’t rely on LLMs for core operations.
    Downloads: 2 This Week
    Last Update:
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