Python Agentic AI Tools

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Browse free open source Python Agentic AI Tools and projects below. Use the toggles on the left to filter open source Python Agentic AI Tools by OS, license, language, programming language, and project status.

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  • 1
    CoPaw

    CoPaw

    Your Personal AI Assistant; easy to install, deploy on local or coud

    CoPaw is a personal AI assistant designed to run on your own machine or in the cloud, giving you full control over memory, models, and data. Built by the AgentScope team, it connects to multiple chat platforms—including DingTalk, Feishu, QQ, Discord, iMessage, and more—through a single unified assistant. CoPaw supports both cloud-based LLM providers and fully local models such as llama.cpp, MLX, and Ollama, allowing you to operate without API keys if preferred. It includes a browser-based Console for chatting, configuring models, managing memory, and extending capabilities with custom skills. With built-in cron scheduling, heartbeat check-ins, and extensible skill loading, CoPaw grows with your workflow over time. Easy installation options—including pip, one-line scripts, Docker, and cloud deployment—make it accessible for both developers and non-technical users.
    Downloads: 38 This Week
    Last Update:
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  • 2
    Claude Skills

    Claude Skills

    Public repository for Agent Skills

    Claude Skills is a public repository that showcases and serves as a collection of skills — modular, reusable packages of instructions, scripts, and resources that Claude and other compatible agents can dynamically discover and load to extend their capabilities on specialized tasks. Rather than relying on handcrafted prompts every time, Skills teach an AI agent procedural knowledge and task-specific workflows so it can apply that expertise reliably, whether the task involves document creation, data analysis, design generation, or technical automation. Each Skill lives in its own directory with a SKILL.md file containing metadata and instructions, and can include supplemental scripts or assets that the agent uses to perform complex operations when relevant.
    Downloads: 21 This Week
    Last Update:
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  • 3
    Browser Use

    Browser Use

    Make websites accessible for AI agents

    Browser-Use is a framework that makes websites accessible for AI agents, enabling automated interactions and data extraction from web pages.
    Downloads: 16 This Week
    Last Update:
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  • 4
    ChemCrow

    ChemCrow

    Chemcrow

    ChemCrow is an AI-powered framework designed to assist in chemical research and discovery. It integrates AI models with chemical knowledge bases to provide intelligent recommendations for synthesis planning, reaction prediction, and material discovery. This tool helps automate and accelerate research in computational chemistry and drug development.
    Downloads: 15 This Week
    Last Update:
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    Access Google's best plus Claude, Llama, and Gemma. Fine-tune and deploy from one console.

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  • 5
    Agent Zero

    Agent Zero

    Agent Zero AI framework

    Agent Zero is not a predefined agentic framework. It is designed to be dynamic, organically growing, and learning as you use it. Agent Zero is fully transparent, readable, comprehensible, customizable and interactive. Agent Zero uses the computer as a tool to accomplish its (your) tasks. Agents can communicate with their superiors and subordinates, asking questions, giving instructions, and providing guidance. Instruct your agents in the system prompt on how to communicate effectively. The terminal interface is real-time streamed and interactive. You can stop and intervene at any point. If you see your agent heading in the wrong direction, just stop and tell it right away. There is a lot of freedom in this framework. You can instruct your agents to regularly report back to superiors asking for permission to continue. You can instruct them to use point-scoring systems when deciding when to delegate subtasks. Superiors can double-check subordinates' results and disputes.
    Downloads: 14 This Week
    Last Update:
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  • 6
    nanobot

    nanobot

    🐈 nanobot: The Ultra-Lightweight Clawdbot / OpenClaw

    nanobot is an ultra-lightweight personal AI assistant designed to deliver powerful agent capabilities without unnecessary complexity. Built in just ~4,000 lines of clean, readable code, it offers a minimalist alternative to heavyweight agent frameworks while retaining core intelligence and extensibility. nanobot is optimized for speed and efficiency, enabling fast startup times and low resource usage across environments. Its research-ready architecture makes it easy for developers to understand, customize, and extend for experimentation or production use. With simple one-click deployment and a straightforward CLI, users can get a working AI assistant running in minutes. Inspired by Clawdbot but radically simplified, nanobot proves that capable AI agents don’t need massive codebases.
    Downloads: 12 This Week
    Last Update:
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  • 7
    ReMe

    ReMe

    Memory Management Kit for Agents

    ReMe is a memory management kit for AI agents that gives them structured, persistent memory capabilities, enabling agents to extract, store, and reuse information across sessions, tasks, and interactions. It is designed to support long-running agent workflows where context matters and working memory alone isn’t enough, helping agents remember user preferences, task histories, and relevant past observations. The toolkit provides APIs to offload large, ephemeral outputs to external storage and reload them on demand, which reduces memory bloat and keeps active context concise. By combining embeddings, vector search, and summarization workflows, ReMe lets developers build agent systems that can recall and apply past knowledge in future reasoning tasks. The project fits into the broader agent-oriented programming ecosystem by supplying a standardized memory layer that integrates with agent frameworks.
    Downloads: 11 This Week
    Last Update:
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  • 8
    OpenManus

    OpenManus

    No fortress, purely open ground. OpenManus is Coming

    OpenManus is an open‑agent AI framework focused on building versatile general-purpose agents capable of autonomously executing complex workflows — such as planning, browsing, tool invocation — all via a pluggable prompts and tools interface. It's being extended with reinforcement learning‑based tuning modules and designed for researchers and developers building custom AI agents.
    Downloads: 10 This Week
    Last Update:
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  • 9
    autoresearch

    autoresearch

    AI agents autonomously run and improve ML experiments overnight

    autoresearch is an experimental framework that enables AI agents to autonomously conduct machine learning research by iteratively modifying and training models. Created by Andrej Karpathy, the project allows an agent to edit the model training code, run short experiments, evaluate results, and repeat the process without human intervention. Each experiment runs for a fixed five-minute training window, enabling rapid iteration and consistent comparison across architectural or hyperparameter changes. The system centers on a simple workflow where the agent modifies a single training file while human researchers guide the process through a program.md instruction file. Designed to run on a single GPU, it keeps the research loop minimal and self-contained to make autonomous experimentation practical. Over time, the agent logs experiments, evaluates improvements, and gradually evolves the model through automated trial-and-error.
    Downloads: 10 This Week
    Last Update:
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  • 10
    npcpy

    npcpy

    The AI toolkit for the AI developer

    npcpy is a Python-based agent framework and command-line toolkit (the NPC Shell) for developers to build, test, and integrate AI agents into their workflows, including both command-line and GUI interfaces via NPC Studio. Welcome to npcpy, the core library of the NPC Toolkit that supercharges natural language processing pipelines and agent tooling. npcpy is a flexible framework for building state-of-the-art applications and conducting novel research with LLMs. The structure of npcpy also allows one to pass an npc to get_llm_response in addition to using the NPC's wrapped method, allowing you to be flexible in your implementation and testing.
    Downloads: 10 This Week
    Last Update:
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  • 11
    DeerFlow

    DeerFlow

    Deep Research framework, combining language models with tools

    DeerFlow is an open-source, community-driven “deep research” framework / multi-agent orchestration platform developed by ByteDance. It aims to combine the reasoning power of large language models (LLMs) with automated tool-use — such as web search, web crawling, Python execution, and data processing — to enable complex, end-to-end research workflows. Instead of a monolithic AI assistant, DeerFlow defines multiple specialized agents (e.g. “planner,” “searcher,” “coder,” “report generator”) that collaborate in a structured workflow, allowing tasks like literature reviews, data gathering, data analysis, code execution, and final report generation to be largely automated. It supports asynchronous task coordination, modular tool integration, and orchestrates the data flow between agents — making it suitable for large-scale or multi-stage research pipelines. Users can deploy it locally or on server infrastructure, integrate custom tools, and benefit from its flexible configuration.
    Downloads: 9 This Week
    Last Update:
    See Project
  • 12
    Open-AutoGLM

    Open-AutoGLM

    An open phone agent model & framework

    Open-AutoGLM is an open-source framework and model designed to empower autonomous mobile intelligent assistants by enabling AI agents to understand and interact with phone screens in a multimodal manner, blending vision and language capability to control real devices. It aims to create an “AI phone agent” that can perceive on-screen content, reason about user goals, and execute sequences of taps, swipes, and text input via automated device control interfaces like ADB, enabling hands-off completion of multi-step tasks such as navigating apps, filling forms, and more. Unlike traditional automation scripts that depend on brittle heuristics, Open-AutoGLM uses pretrained large language and vision-language models to interpret visual context and natural language instructions, giving the agent robust adaptability across apps and interfaces.
    Downloads: 9 This Week
    Last Update:
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  • 13
    PraisonAI

    PraisonAI

    PraisonAI application combines AutoGen and CrewAI or similar framework

    PraisonAI application combines AutoGen and CrewAI or similar frameworks into a low-code solution for building and managing multi-agent LLM systems, focusing on simplicity, customization, and efficient human-agent collaboration. Chat with your ENTIRE Codebase. Praison AI, leveraging both AutoGen and CrewAI or any other agent framework, represents a low-code, centralized framework designed to simplify the creation and orchestration of multi-agent systems for various LLM applications, emphasizing ease of use, customization, and human-agent interaction.
    Downloads: 9 This Week
    Last Update:
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  • 14
    Self-Operating Computer

    Self-Operating Computer

    A framework to enable multimodal models to operate a computer

    The Self-Operating Computer Framework is an innovative system that enables multimodal models to autonomously operate a computer by interpreting the screen and executing mouse and keyboard actions to achieve specified objectives. This framework is compatible with various multimodal models and currently integrates with GPT-4o, o1, Gemini Pro Vision, Claude 3, and LLaVa. Notably, it was the first known project to implement a multimodal model capable of viewing and controlling a computer screen. The framework supports features like Optical Character Recognition (OCR) and Set-of-Mark (SoM) prompting to enhance visual grounding capabilities. It is designed to be compatible with macOS, Windows, and Linux (with X server installed), and is released under the MIT license.
    Downloads: 9 This Week
    Last Update:
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  • 15
    AgentScope

    AgentScope

    Build and run agents you can see, understand and trust

    AgentScope is a production-ready agent framework designed to help developers build, deploy, and scale intelligent agentic applications. It provides essential abstractions that evolve with advancing LLM capabilities, emphasizing reasoning, tool use, and flexible orchestration rather than rigid prompt constraints. With built-in support for ReAct agents, memory, planning, human-in-the-loop control, and real-time voice interaction, developers can create powerful agents in minutes. AgentScope integrates seamlessly with tools, long-term memory systems, MCP, A2A (Agent-to-Agent) protocols, and observability frameworks. It also supports reinforcement learning workflows for tuning agents and improving performance across complex tasks. Deployable locally, serverless in the cloud, or on Kubernetes with OpenTelemetry support, AgentScope is built for both experimentation and production environments.
    Downloads: 8 This Week
    Last Update:
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  • 16
    DB-GPT

    DB-GPT

    Revolutionizing Database Interactions with Private LLM Technology

    DB-GPT is an experimental open-source project that uses localized GPT large models to interact with your data and environment. With this solution, you can be assured that there is no risk of data leakage, and your data is 100% private and secure.
    Downloads: 8 This Week
    Last Update:
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  • 17
    Langroid

    Langroid

    Harness LLMs with Multi-Agent Programming

    Given the remarkable abilities of recent Large Language Models (LLMs), there is an unprecedented opportunity to build intelligent applications powered by this transformative technology. The top question for any enterprise is: how best to harness the power of LLMs for complex applications? For technical and practical reasons, building LLM-powered applications is not as simple as throwing a task at an LLM system and expecting it to do it. Effectively leveraging LLMs at scale requires a principled programming framework. In particular, there is often a need to maintain multiple LLM conversations, each instructed in different ways, and "responsible" for different aspects of a task.
    Downloads: 8 This Week
    Last Update:
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  • 18
    MetaGPT

    MetaGPT

    The Multi-Agent Framework

    The Multi-Agent Framework: Given one line Requirement, return PRD, Design, Tasks, Repo. Assign different roles to GPTs to form a collaborative software entity for complex tasks. MetaGPT takes a one-line requirement as input and outputs user stories / competitive analysis/requirements/data structures / APIs / documents, etc. Internally, MetaGPT includes product managers/architects/project managers/engineers. It provides the entire process of a software company along with carefully orchestrated SOPs.
    Downloads: 8 This Week
    Last Update:
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  • 19
    OpenAI Python

    OpenAI Python

    The official Python library for the OpenAI API

    The OpenAI Python library provides convenient access to the OpenAI REST API from any Python 3.7+ application. The library includes type definitions for all request params and response fields, and offers both synchronous and asynchronous clients powered by httpx.
    Downloads: 8 This Week
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  • 20
    OpenSandbox

    OpenSandbox

    OpenSandbox is a general-purpose sandbox platform for AI applications

    OpenSandbox is a general purpose sandbox platform designed to securely run and isolate AI applications and untrusted workloads in controlled environments. The project focuses on providing a unified sandbox API that simplifies the process of executing code safely across different runtime backends. It supports multiple programming languages through SDKs, allowing developers to integrate sandbox capabilities into their systems without building custom isolation layers. The platform is built to work with container technologies such as Docker and Kubernetes, enabling scalable and production ready deployments. OpenSandbox is particularly useful for AI agents, code execution services, and any scenario where untrusted code must be executed safely. Its architecture emphasizes flexibility, security boundaries, and operational consistency across environments. Overall, the project aims to standardize sandbox execution for modern AI and cloud native workflows.
    Downloads: 8 This Week
    Last Update:
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  • 21
    AutoGPT

    AutoGPT

    Powerful tool that lets you create and run intelligent agents

    AutoGPT is an experimental open-source application showcasing the capabilities of the GPT-4 language model. This program, driven by GPT-4, chains together LLM "thoughts", to autonomously achieve whatever goal you set. As one of the first examples of GPT-4 running fully autonomously, AutoGPT pushes the boundaries of what is possible with AI.
    Downloads: 7 This Week
    Last Update:
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  • 22
    gpt-engineer

    gpt-engineer

    Full stack AI software engineer

    gpt-engineer is an open-source platform designed to help developers automate the software development process using natural language. The platform allows users to specify software requirements in plain language, and the AI generates and executes the corresponding code. It can also handle improvements and iterative development, giving users more control over the software they’re building. Built with a terminal-based interface, gpt-engineer is customizable, enabling developers to experiment with AI-assisted programming and refine their development process. It is especially useful for automating the coding and iterative feedback loop in software development.
    Downloads: 7 This Week
    Last Update:
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  • 23
    Aden Hive

    Aden Hive

    Outcome driven agent development framework that evolves

    Hive is an open-source agent development framework that helps developers build autonomous, reliable, self-improving AI agents by letting them describe goals in ordinary natural language instead of hand-coding detailed workflows. Rather than manually defining execution graphs, Hive’s coding agent generates the agent graph, connection code, and test cases based on your high-level objectives, enabling outcome-driven agent creation that fits real business processes. Once deployed, agents can capture failure data, evolve automatically to meet their success criteria, and redeploy without constant manual intervention, delivering continual improvement over time. The framework also includes human-in-the-loop nodes, credential management, cost and budget controls, and real-time observability so teams can monitor execution and intervene as needed. Hive is designed for production environments and supports a wide range of large language models, local models, and business system connectivity.
    Downloads: 6 This Week
    Last Update:
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  • 24
    AgentForge

    AgentForge

    Extensible AGI Framework

    AgentForge is a framework for creating and deploying AI agents that can perform autonomous decision-making and task execution. It enables developers to define agent behaviors, train models, and integrate AI-powered automation into various applications.
    Downloads: 6 This Week
    Last Update:
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  • 25
    Flowly AI

    Flowly AI

    Flowly is 100x faster than OpenClaw

    FlowlyAI, as suggested by the repository name, appears to be a project aimed at building tools or frameworks that harness artificial intelligence to automate and streamline workflows, though the GitHub repository itself does not have a strong public description available. Based on the name, it likely focuses on enabling developers or teams to define, orchestrate, and execute AI-driven processes, perhaps combining data inputs, model calls, and conditional logic into reusable flows. Projects like this often include a set of components for creating modular AI tasks, connecting data sources, and integrating with APIs so that complex automation can run with minimal boilerplate. Given the broader context of AI workflow tools, FlowlyAI might emphasize extensibility, allowing users to plug in different models or custom logic blocks depending on their specific use cases.
    Downloads: 6 This Week
    Last Update:
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