Python Agentic AI Tools

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Browse free open source Python Agentic AI Tools and projects below. Use the toggles on the left to filter open source Python Agentic AI Tools by OS, license, language, programming language, and project status.

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  • 1
    Claw Code

    Claw Code

    AI agent harness for AI coding agents

    Claw Code is an open-source AI agent harness project focused on building better tools for orchestrating and managing autonomous coding agents. It originated as a clean-room reimplementation inspired by the architecture of Claude Code, aiming to replicate core concepts without using proprietary code. The project provides a Python-based foundation for experimenting with agent workflows, tool integration, and task execution pipelines. It emphasizes harness engineering—how agents are structured, how they interact with tools, and how they maintain context during execution. The system is being actively expanded, with a Rust-based runtime in development to improve performance and memory safety. Overall, Claw Code serves as a research-driven platform for advancing agent-based software development systems.
    Downloads: 679 This Week
    Last Update:
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  • 2
    OpenJarvis

    OpenJarvis

    Personal AI, On Personal Devices

    OpenJarvis is an open-source framework designed to build personal AI agents that run primarily on local devices rather than relying on cloud infrastructure. Developed as part of the Intelligence Per Watt research initiative, it focuses on improving the efficiency and practicality of on-device AI systems. The framework provides shared primitives for building local-first agents, along with evaluation tools that measure performance using metrics such as energy consumption, latency, cost, and accuracy. OpenJarvis integrates with local inference engines like Ollama, vLLM, SGLang, and llama.cpp to run language models directly on personal hardware. It also includes a learning loop that allows models to improve over time using locally generated interaction traces. By prioritizing local execution and efficiency, OpenJarvis aims to provide a foundation for privacy-preserving personal AI assistants.
    Downloads: 51 This Week
    Last Update:
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  • 3
    DeerFlow

    DeerFlow

    Deep Research framework, combining language models with tools

    DeerFlow is an open-source, community-driven “deep research” framework / multi-agent orchestration platform developed by ByteDance. It aims to combine the reasoning power of large language models (LLMs) with automated tool-use — such as web search, web crawling, Python execution, and data processing — to enable complex, end-to-end research workflows. Instead of a monolithic AI assistant, DeerFlow defines multiple specialized agents (e.g. “planner,” “searcher,” “coder,” “report generator”) that collaborate in a structured workflow, allowing tasks like literature reviews, data gathering, data analysis, code execution, and final report generation to be largely automated. It supports asynchronous task coordination, modular tool integration, and orchestrates the data flow between agents — making it suitable for large-scale or multi-stage research pipelines. Users can deploy it locally or on server infrastructure, integrate custom tools, and benefit from its flexible configuration.
    Downloads: 50 This Week
    Last Update:
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  • 4
    Claude Skills

    Claude Skills

    Public repository for Agent Skills

    Claude Skills is a public repository that showcases and serves as a collection of skills — modular, reusable packages of instructions, scripts, and resources that Claude and other compatible agents can dynamically discover and load to extend their capabilities on specialized tasks. Rather than relying on handcrafted prompts every time, Skills teach an AI agent procedural knowledge and task-specific workflows so it can apply that expertise reliably, whether the task involves document creation, data analysis, design generation, or technical automation. Each Skill lives in its own directory with a SKILL.md file containing metadata and instructions, and can include supplemental scripts or assets that the agent uses to perform complex operations when relevant.
    Downloads: 49 This Week
    Last Update:
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  • 5
    AutoResearchClaw

    AutoResearchClaw

    Autonomous research from idea to paper. Chat an Idea. Get a Paper 🦞

    AutoResearchClaw is an open-source framework designed to automatically generate full academic research papers from a single idea or topic. Built in Python, it orchestrates a multi-stage research pipeline that gathers literature, formulates hypotheses, runs experiments, analyzes results, and writes the final paper. The system retrieves real academic references from sources such as arXiv and Semantic Scholar to ensure credible citations. It can automatically generate code for experiments, run them in a sandbox environment, and analyze the results with statistical methods. The platform also uses multi-agent debate and automated peer review processes to refine research findings and improve paper quality. By combining literature discovery, experimentation, and writing automation, AutoResearchClaw aims to turn research ideas into conference-ready papers with minimal human intervention.
    Downloads: 37 This Week
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  • 6
    Agent Zero

    Agent Zero

    Agent Zero AI framework

    Agent Zero is not a predefined agentic framework. It is designed to be dynamic, organically growing, and learning as you use it. Agent Zero is fully transparent, readable, comprehensible, customizable and interactive. Agent Zero uses the computer as a tool to accomplish its (your) tasks. Agents can communicate with their superiors and subordinates, asking questions, giving instructions, and providing guidance. Instruct your agents in the system prompt on how to communicate effectively. The terminal interface is real-time streamed and interactive. You can stop and intervene at any point. If you see your agent heading in the wrong direction, just stop and tell it right away. There is a lot of freedom in this framework. You can instruct your agents to regularly report back to superiors asking for permission to continue. You can instruct them to use point-scoring systems when deciding when to delegate subtasks. Superiors can double-check subordinates' results and disputes.
    Downloads: 36 This Week
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  • 7
    OpenManus

    OpenManus

    Open-source AI agent framework

    OpenManus is an open-source AI agent framework designed to autonomously execute complex, multi-step tasks by combining reasoning, planning, and tool use. It enables developers to build agents that can think, act, and iterate toward goals rather than simply responding to prompts. The platform emphasizes task decomposition, allowing agents to break down objectives into smaller steps and execute them sequentially or recursively. OpenManus supports integration with external tools, APIs, and environments, making it suitable for real-world automation workflows. It is built to be flexible and extensible, enabling customization of agent behaviors, tools, and reasoning strategies. Overall, OpenManus provides a foundation for creating more capable, autonomous AI systems that can handle dynamic and goal-driven tasks.
    Downloads: 36 This Week
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  • 8
    CoPaw

    CoPaw

    Your Personal AI Assistant; easy to install, deploy on local or coud

    CoPaw is a personal AI assistant designed to run on your own machine or in the cloud, giving you full control over memory, models, and data. Built by the AgentScope team, it connects to multiple chat platforms—including DingTalk, Feishu, QQ, Discord, iMessage, and more—through a single unified assistant. CoPaw supports both cloud-based LLM providers and fully local models such as llama.cpp, MLX, and Ollama, allowing you to operate without API keys if preferred. It includes a browser-based Console for chatting, configuring models, managing memory, and extending capabilities with custom skills. With built-in cron scheduling, heartbeat check-ins, and extensible skill loading, CoPaw grows with your workflow over time. Easy installation options—including pip, one-line scripts, Docker, and cloud deployment—make it accessible for both developers and non-technical users.
    Downloads: 19 This Week
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  • 9
    MoneyPrinter V2

    MoneyPrinter V2

    Automate the process of making money online

    MoneyPrinter V2 is an open-source automation platform designed to streamline and scale online income generation workflows by combining content creation, social media automation, and marketing strategies into a single system. It is a complete rewrite of the original MoneyPrinter project, focusing on modularity, extensibility, and broader functionality across multiple monetization channels. The platform operates primarily through Python-based scripts that automate tasks such as generating and publishing YouTube Shorts, posting on social media platforms like Twitter, and executing affiliate marketing campaigns. It integrates scheduling mechanisms that allow users to run automated workflows at defined intervals, enabling continuous content production and distribution without manual intervention.
    Downloads: 17 This Week
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  • 10
    AutoGPT

    AutoGPT

    Powerful tool that lets you create and run intelligent agents

    AutoGPT is an experimental open-source application showcasing the capabilities of the GPT-4 language model. This program, driven by GPT-4, chains together LLM "thoughts", to autonomously achieve whatever goal you set. As one of the first examples of GPT-4 running fully autonomously, AutoGPT pushes the boundaries of what is possible with AI.
    Downloads: 15 This Week
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  • 11
    Hermes Agent

    Hermes Agent

    The agent that grows with you

    Hermes Agent is a fully open-source autonomous AI agent designed to run persistently on your own machine or server, becoming more capable the longer it operates by learning from experience and building reusable procedural skills. Rather than functioning as a stateless chatbot, it maintains long-term memory across sessions and can generate searchable “Skill Documents” that capture how it solved complex tasks so it doesn’t start from scratch each time. The agent interfaces with messaging platforms like Telegram, Discord, Slack, and WhatsApp through a single gateway process, and also offers an interactive terminal user interface with history, autocomplete, and streamable tool output. It supports scheduled automation in natural language, allowing users to set up recurring tasks such as daily briefings or system audits that it runs unattended.
    Downloads: 14 This Week
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  • 12
    Claw Compactor

    Claw Compactor

    14-stage Fusion Pipeline for LLM token compression

    Claw Compactor is a utility designed to optimize and manage the context limitations inherent in AI agent systems, particularly those built on OpenClaw-like architectures. It addresses the challenge of finite context windows in language models by compressing or summarizing historical interactions while preserving essential information. The system works by transforming older conversation data into condensed representations that maintain continuity without exceeding token limits. This approach allows long-running agent sessions to continue operating efficiently without losing critical context. It is especially useful in autonomous workflows where agents accumulate large volumes of interaction history over time. The project aligns with broader strategies in AI systems that balance memory retention with computational constraints. Overall, claw-compactor functions as an infrastructure component that enhances scalability and stability in persistent AI agent environments.
    Downloads: 13 This Week
    Last Update:
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  • 13
    Self-Operating Computer

    Self-Operating Computer

    A framework to enable multimodal models to operate a computer

    The Self-Operating Computer Framework is an innovative system that enables multimodal models to autonomously operate a computer by interpreting the screen and executing mouse and keyboard actions to achieve specified objectives. This framework is compatible with various multimodal models and currently integrates with GPT-4o, o1, Gemini Pro Vision, Claude 3, and LLaVa. Notably, it was the first known project to implement a multimodal model capable of viewing and controlling a computer screen. The framework supports features like Optical Character Recognition (OCR) and Set-of-Mark (SoM) prompting to enhance visual grounding capabilities. It is designed to be compatible with macOS, Windows, and Linux (with X server installed), and is released under the MIT license.
    Downloads: 13 This Week
    Last Update:
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  • 14
    OpenClaw Medical Skills

    OpenClaw Medical Skills

    The largest open-source medical AI skills library for OpenClaw

    OpenClaw-Medical-Skills is an open-source library that provides a large collection of specialized medical capabilities designed for the OpenClaw AI agent ecosystem. The project organizes domain-specific “skills” that enable autonomous agents to perform tasks related to biomedical research, healthcare analysis, and clinical data interpretation. Each skill is packaged as a modular component that can be integrated into an OpenClaw-based AI assistant, allowing the agent to perform expert-level reasoning and workflows in medical contexts. Instead of relying on general-purpose language model responses, the repository equips AI agents with structured instructions and tools tailored to medical knowledge and datasets. This modular design allows developers and researchers to build AI systems that can access specialized medical reasoning processes, retrieve relevant biomedical information, and generate structured outputs suitable for analysis or downstream processing.
    Downloads: 12 This Week
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  • 15
    LangGraph

    LangGraph

    Build resilient language agents as graphs

    LangGraph is a library for building stateful, multi-actor applications with LLMs, used to create agent and multi-agent workflows. Compared to other LLM frameworks, it offers these core benefits: cycles, controllability, and persistence. LangGraph allows you to define flows that involve cycles, essential for most agentic architectures, differentiating it from DAG-based solutions. As a very low-level framework, it provides fine-grained control over both the flow and state of your application, crucial for creating reliable agents. Additionally, LangGraph includes built-in persistence, enabling advanced human-in-the-loop and memory features.
    Downloads: 9 This Week
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  • 16
    MedgeClaw

    MedgeClaw

    Open-source AI research assistant for biomedicine

    MedgeClaw is a specialized AI-powered research assistant tailored for biomedical and scientific workflows, built on top of OpenClaw and Claude Code architectures. It integrates a large library of domain-specific skills, enabling it to perform complex analyses in areas such as genomics, drug discovery, and clinical research. The system connects conversational interfaces with computational environments, allowing users to initiate research tasks through messaging platforms while the backend executes analyses using tools like R and Python. It includes a real-time dashboard that displays progress, generated code, and outputs, providing transparency throughout the research process. MedgeClaw also supports reproducibility by generating structured reports and maintaining consistent environments through containerization. Its architecture combines conversational AI, automated pipelines, and scientific tooling into a unified workflow.
    Downloads: 9 This Week
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  • 17
    OpenAI Python

    OpenAI Python

    The official Python library for the OpenAI API

    The OpenAI Python library provides convenient access to the OpenAI REST API from any Python 3.7+ application. The library includes type definitions for all request params and response fields, and offers both synchronous and asynchronous clients powered by httpx.
    Downloads: 9 This Week
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  • 18
    Agent S

    Agent S

    Agent S: an open agentic framework that uses computers like a human

    Agent S is an open-source agentic framework designed to enable autonomous computer use through an Agent-Computer Interface (ACI). Built to operate graphical user interfaces like a human, it allows AI agents to perceive screens, reason about tasks, and execute actions across macOS, Windows, and Linux systems. The latest version, Agent S3, surpasses human-level performance on the OSWorld benchmark, demonstrating state-of-the-art results in complex multi-step computer tasks. Agent S combines powerful foundation models (such as GPT-5) with grounding models like UI-TARS to translate visual inputs into precise executable actions. It supports flexible deployment via CLI, SDK, or cloud, and integrates with multiple model providers including OpenAI, Anthropic, Gemini, Azure, and Hugging Face endpoints. With optional local code execution, reflection mechanisms, and compositional planning, Agent S provides a scalable and research-driven framework for building advanced computer-use agents.
    Downloads: 8 This Week
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  • 19
    OpenHands

    OpenHands

    Open-source autonomous AI software engineer

    Welcome to OpenHands (formerly OpenDevin), an open-source autonomous AI software engineer who is capable of executing complex engineering tasks and collaborating actively with users on software development projects. Use AI to tackle the toil in your backlog, so you can focus on what matters: hard problems, creative challenges, and over-engineering your dotfiles We believe agentic technology is too important to be controlled by a few corporations. So we're building all our agents in the open on GitHub, under the MIT license. Our agents can do anything a human developer can: they write code, run commands, and use the web. We're partnering with AI safety experts like Invariant Labs to balance innovation with security.
    Downloads: 8 This Week
    Last Update:
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  • 20
    Open-AutoGLM

    Open-AutoGLM

    An open phone agent model & framework

    Open-AutoGLM is an open-source framework and model designed to empower autonomous mobile intelligent assistants by enabling AI agents to understand and interact with phone screens in a multimodal manner, blending vision and language capability to control real devices. It aims to create an “AI phone agent” that can perceive on-screen content, reason about user goals, and execute sequences of taps, swipes, and text input via automated device control interfaces like ADB, enabling hands-off completion of multi-step tasks such as navigating apps, filling forms, and more. Unlike traditional automation scripts that depend on brittle heuristics, Open-AutoGLM uses pretrained large language and vision-language models to interpret visual context and natural language instructions, giving the agent robust adaptability across apps and interfaces.
    Downloads: 7 This Week
    Last Update:
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  • 21
    gpt-engineer

    gpt-engineer

    Full stack AI software engineer

    gpt-engineer is an open-source platform designed to help developers automate the software development process using natural language. The platform allows users to specify software requirements in plain language, and the AI generates and executes the corresponding code. It can also handle improvements and iterative development, giving users more control over the software they’re building. Built with a terminal-based interface, gpt-engineer is customizable, enabling developers to experiment with AI-assisted programming and refine their development process. It is especially useful for automating the coding and iterative feedback loop in software development.
    Downloads: 7 This Week
    Last Update:
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  • 22
    nanobot

    nanobot

    🐈 nanobot: The Ultra-Lightweight Clawdbot / OpenClaw

    nanobot is an ultra-lightweight personal AI assistant designed to deliver powerful agent capabilities without unnecessary complexity. Built in just ~4,000 lines of clean, readable code, it offers a minimalist alternative to heavyweight agent frameworks while retaining core intelligence and extensibility. nanobot is optimized for speed and efficiency, enabling fast startup times and low resource usage across environments. Its research-ready architecture makes it easy for developers to understand, customize, and extend for experimentation or production use. With simple one-click deployment and a straightforward CLI, users can get a working AI assistant running in minutes. Inspired by Clawdbot but radically simplified, nanobot proves that capable AI agents don’t need massive codebases.
    Downloads: 7 This Week
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  • 23
    notebooklm-py

    notebooklm-py

    Unofficial Python API and agentic skill for Google NotebookLM

    notebooklm-py is an unofficial Python API and agent-ready integration layer for Google NotebookLM that exposes NotebookLM functionality through code, the command line, and AI agent workflows. Its goal is to provide programmatic access not just to standard notebook operations, but also to many capabilities that are either limited or unavailable in the web interface, making it especially useful for automation and custom pipelines. The project covers notebook management, source ingestion, conversational querying, research workflows, and sharing controls, while also enabling the generation of a wide range of study and media artifacts. These outputs include audio overviews, videos, slide decks, infographics, quizzes, flashcards, reports, data tables, and mind maps, with configurable formats and export options.
    Downloads: 7 This Week
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  • 24
    AskUI Vision Agent

    AskUI Vision Agent

    Enable AI to control your desktop, mobile and HMI devices

    AskUI’s Vision Agent is an automation framework that allows you—and AI agents—to control real desktops, mobile devices, and HMI systems by perceiving the UI and performing actions like clicking, typing, scrolling, and drag-and-drop. It is designed for multi-platform compatibility and supports multiple AI models so you can tailor perception and decision-making to your workload. The repository presents a feature overview, sample media, and frequent release notes, which show ongoing improvements such as CORS checks and other operational tweaks. The broader AskUI documentation covers the Python Vision Agent along with suite services and inference APIs, indicating a productized ecosystem rather than a single library. Community-curated lists also recognize Vision Agent as part of the broader “GUI agents” landscape, placing it among other computer-use agents.
    Downloads: 6 This Week
    Last Update:
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  • 25
    ChemCrow

    ChemCrow

    Chemcrow

    ChemCrow is an AI-powered framework designed to assist in chemical research and discovery. It integrates AI models with chemical knowledge bases to provide intelligent recommendations for synthesis planning, reaction prediction, and material discovery. This tool helps automate and accelerate research in computational chemistry and drug development.
    Downloads: 6 This Week
    Last Update:
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