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A Linux Proaudio FrameWork with improved Wine/kernel(rt) support
...Custom version of Wine with a delta of patches to ensure Wine is ready for proaudio on the linux platform. It's also has various other improvements and bug fixes.
You'll want both WineASIO and FSThost;
WineASIO - WineASIO provides an ASIO to JACK driver for WINE.
https://sourceforge.net/projects/wineasio/
FSThost - FreeST standalone fork; wraps windows VSTs (.dll) into standalone apps / jack clients. + other useful features.
https://sourceforge.net/projects/fsthost/
* visit the L_pa wiki pages for more info on usage / other info.
WineASIO provides an ASIO to JACK driver for WINE. ASIO is the most common Windows low-latency driver, so is commonly used in audio workstation programs.
For best results with Ubuntu, install the kxstudio repos - http://kxstudio.sourceforge.net/ - and install wineasio from there.