chimera
ChiMera: An easy-to-use pipeline for Genome-based Metabolic Network re
There is a scarcity of user-friendly tools that can be used in daily routine, providing insights about the metabolic network of a target organism for researcher’s groups.
Here we present a novel tool, Chimera, which combines the most efficient tools in model reconstruction, prediction, and visualization and also implements new in-house algorithms for database integration and data manipulation.
Our goals:
Produce an organism-specific model based on the CarveMe algorithm
Manage the model and perform growth predictions with COBRApy
Create visualization for the metabolic network using PSAMM and Escher
Add pathway information to metabolic maps using in house algorithm
Perform single and double, gene and reaction, knockout in the organism