mapDIA
Model-based Analysis of quantitative Proteomics data in DIA-MS
mapDIA performs essential data preprocessing, including novel retention time-based normalization method and a sequence of peptide/fragment selection steps, and more importantly, hierarchical model-based statistical significance analysis for multi-group comparisons under representative experimental designs. The advanced modelling technique also allows the user to incorporate relational information such as existing network data or protein-peptide mapping, enabling module-oriented analysis...